From: chemistry-request at
To: chemistry-request at
Date: Wed Mar 2 14:51:02 2011
Subject: 11.06.08 Course: Identification of Druggable Sites for Protein-Protein Interaction Targets, Cambridge, MA
When: June 8, 2011 (6:00 - 9:00 p.m.)
Where: Royal Sonesta Hotel Boston, Cambridge, Massachusetts

Topics covered:
* The problem of disrupting protein-protein interactions 
* Predicting the structure of protein-protein complexes using fragment-based identification of binding hot spots 
* Druggability of binding sites determined by the hot spots 
* Identification of functional groups with preferential binding to hot spots 
* Comparison of computational and experimental approaches. 

Course Instructors:
Sandor Vajda, Ph.D., Professor, Departments of Biomedical Engineering and Chemistry, Boston University
Dima Kozakov, Ph.D., Research Assistant Professor, Departments of Biomedical Engineering, Boston University

More course details:

This course will be held at the conclusion of day one of CHI's Structure-Based Drug Design conference that 
will be held on June 6-8, 2011 at the Royal Sonesta Hotel Boston in Cambridge, Massachusetts. A separate
registration is required to attend the conference.
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