From: jobs at ccl.net (do not send your application there!!!)<br />
To: jobs at ccl.net<br />
Date: Thu Feb 28 06:07:53 2008<br />
Subject: <STRONG>08.02.27 COMPUTATIONAL CHEMISTRY AND BIOLOGY OPPORTUNITIES AT D. E. SHAW RESEARCH</STRONG><br />

<pre>Extraordinarily gifted computational chemists, biologists, and other computational 
scientists are sought to join a rapidly growing New York-based research group 
that is pursuing an ambitious, long-term strategy aimed at fundamentally 
transforming the process of drug discovery.

Candidates should have world-class credentials in computational chemistry, 
biology, or physics, or in a relevant area of computer science or applied 
mathematics, and must have unusually strong research skills.  Relevant areas 
of experience might include protein structure prediction, the computation of 
protein-ligand binding affinities, the study of biologically important systems 
using molecular dynamics and/or Monte Carlo simulation, and the application of 
statistical mechanics to biomolecular systemsbut specific knowledge of any of 
these areas is less critical than exceptional intellectual ability and a 
demonstrated track record of achievement.  Current areas of interest within 
the group include molecular dynamics simulation of functionally significant 
globular and membrane proteins, the prediction of protein structures and binding 
free energies, structure- and ligand-based drug design, characterization of 
protein-protein, protein-nucleic acid and protein-lipid interactions, and 
the development of algorithms for biomolecular simulations.

This research effort is being financed by the D. E. Shaw group, a global 
investment and technology development firm with more than US $30 billion in 
aggregate investment capital.  The project was initiated by the firm's 
founder, Dr. David E. Shaw, and operates under his direct scientific leadership.  

We are eager to add both senior- and junior-level members to our world-class 
team, and are prepared to offer above-market compensation to candidates of 
truly exceptional ability. 

Please send your curriculum vitae (including list of publications, thesis 
topic, and advisor, if applicable) to ccl-chem a career.DEShawResearch.com.

D. E. Shaw Research does not discriminate in employment matters on the basis 
of race, color, religion, gender, pregnancy, national origin, age, military 
service eligibility, veteran status, sexual orientation, marital status, 
disability, or any other protected class.</pre>
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