When do discoveries become miracles?

Touching the lives of millions of people everywhere. Reaching beyond the ordinary to make an impact on something greater than the bottom line. Playing a key role in some of the most critical issues facing healthcare today.

We are Pfizer Global Research & Development (PGRD), the largest pharmaceutical R&D organization in the world. As Pfizer’s visionary discovery and development division, innovation shapes our strategy, defines our purpose and governs every facet of our operations - from the research and development that leads to pharmaceutical breakthroughs to the way we respond to the changing marketplace.

Our emphasis on innovation has enabled us to bring to market a wide range of outstanding medicines, such as Lipitor, Zithromax, Viracept, Zoloft, Viagra and our newest smoking cessation medicine, Chantix. But we recognize that there is much, much more work to be done, and we look forward to conquering the challenges facing global healthcare. Today, our research pipeline spans many therapeutic areas and research projects and we’re committed to bringing even more miracles to the marketplace. Here, we imagine that our world can be a healthier and happier place for all.

We currently have the following opportunity:

Computational Chemist R4/R5

The primary responsibilities of this position are for discovery and implementation of novel computational methods, analyses, and workflows that ultimately accelerate the delivery of products and projects against Research milestones. Research activities could include identification of novel methods for lead transformation, reaction-based template design for parallel synthesis, virtual screening, structure-based design, scoring function design, or in silico predictive methods for improvement of ADMET characteristics.

The position requires a Ph.D. in a computational science-based discipline or equivalent, plus 3+ years of relevant industry experience. Advanced knowledge of computational chemistry principles and knowledge of how to apply these techniques to pharmaceutical research projects is required, as well as knowledge of pharmaceutical drug discovery and development processes, molecular design and optimization principles, and downstream property optimizations that enable successful drug candidates. A strong background in chemistry, and especially parallel chemistry design methods, is also required. Technical qualifications include good scientific computing experience with programming languages such as Java or C++, relational database tools, operating systems such as Linux and Windows, and/or web application development tools.

Job Requisition #: 78756, La Jolla, CA

To learn more about our people, our products, and our plans for the future, visit www.pfizer.com/careers

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Pfizer in the U.S.