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To: jobs at ccl.net
Date: Fri Oct 20 13:58:25 2017
Subject: 17.10.20 Computational study of folding and assembly of virus-like particles, KIT, Karlsruhe, Germany
Computational study of folding and assembly of virus-like particles
Scientist (f/m) 50% part time / discipline physics or chemistry
Karlsruhe Institute of Technology, Germany

Description
The Nanoscale and Biomolecular Simulation group ( http://www.int.kit.edu/wenzel.php ) at the Institute of Nanotechnology is seeking a scientist (f/m) for a DFG funded collaborative research project on the development of novel vaccines for diseases such as cancer or HIV. The idea is to modify virus capsids, so call virus like particles (VLP), in such way that they stimulate the immune response against the targeted disease.
The project involves working as part of an interdisciplinary team with the final aim of computationally predict the folding and assembly properties of the virus like particle after its constituent proteins have been genetically modified to accomplish its purpose. You will develop and apply computational models and simulation for protein structure prediction, folding and assembly to help optimize the processing of the vaccine and optimize its function. The project is carried out in close collaboration with an experimental group that maintains and investigates an extensive library of VLP. Our group is focused on the state of art computational methods at the interface of physics, chemistry, biology and material science.

In addition to the direct scientific work, this position offers the possibility to earn a PhD.

Requirements
Applicants (f/m) are required to have completed a master degree at a university in physics or chemistry or a related discipline with a particular interest in Thermodynamics. Computer programming skills and knowledge of molecular simulation methods are of great advantage. Applicants are further required to be able to fluently communicate in the English language.

Salary
Salary category 13, depending on the fulfillment of professional and personal requirements.

Contact person in line-management
For further information, please contact Prof. Dr. Wenzel, E-Mail: wolfgang.wenzel/./kit.edu .

Application
The contract is limited to 3 years. Application is possible up to 30.10.2017.
For details on how to apply online, please visit: https://www.pse.kit.edu/karriere/joboffer.php?id=918



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