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Date: Mon May 14 09:19:28 2018
Subject: 18.05.14 EARLY STAGE RESEARCHER / PhD POSITION ADVANCED COMPUTATIONAL STUDIES OF STRUCTURAL DYNAMICS OF DNA AND RNA SYSTEMS, CEITEC MU, Brno, CZ
An Early Stage Researcher position is available in Jiri Sponer lab
(http://www.ibp.cz/en/departments/structure-and-dynamics-of-nucleic-acids/info-about-the-department/; 
CEITEC, Masaryk University, Brno, Czech Republic) to participate in 
the research focused on Multiscale theoretical and computational studies 
(using explicit-solvent atomistic molecular dynamics simulation methods 
and quantum chemistry) of DNA and RNA molecules, and their molecular 
interactions with proteins and ligands, with a specific emphasis given to 
non-canonical molecules such as guanine quadruplexes or folded RNA molecules.
The research can be focused on applications as well as method development, in
the latter case with emphasis given to development and testing of the 
simulation force fields.

Requirements: 
Equivalent to a Czech Master's degree (Mgr., Ing., MSc.) from an 
 institution of recognized standing (four or five-year undergraduate degree), 
 must have no more than 4 years of full-time research experience, and must not
 have been awarded a doctoral degree at the time of recruitment
Prior experience in computational studies of nucleic acids (preferable) 
 or proteins, including a relevant research publication in the field 
Spent at least 2 whole years out of the last 3 outside the Czech Republic
Good English language  spoken and written 

We offer: 
Enrolment in CEITEC PhD School (detailed information available at: 
 http://ls-phd.ceitec.cz/) and a diverse training programme of the 
 LightDyNAmics Marie Sklodowska-Curie European Training Network (MSCA-ETN)
Interesting position in a dynamically expanding research institute 
An attractive salary and benefits package within the MSCA-ETN 
 LightDyNAmics (2300 EUR gross salary plus 370 EUR family contribution if 
 applicable). Current average gross salary in the  Czech Republic is 
 28700 CZK (1130 EUR), the minimum salary is 12.200 CZK (480 EUR)
Background of a recognized and successful institution with supportive 
 and international working environment
Environment promoting interdisciplinarity and intersectorality of 
 research
Excellent in-house computational facilities and direct collaboration 
 with experimental laboratories
Experienced research team covering a broad range of topics and 
 computational methodologies
Involvement in prestigious international ITN research training network
Support for the relocation process (welcome office service)
6 weeks of paid holiday


LighDyNAmics Marie-Skodowska-Curie European Training Network
The main goal of LightDyNAmics is to achieve a complete understanding of 
the ultrafast dynamical processes at the molecular scale induced 
by UV light absorption in DNA and to unveil the mechanisms leading 
to photodamage of the genetic code. LightDyNAmics is an academia-industry 
research environment training 15 Early Stage Researchers (ESRs) by 
crossing the traditional border between theoretical and experimental 
expertise. This will be achieved by performing independent, yet 
interrelated and complementary research projects focussed on 
photoactivated dynamics of DNA, and by developing a variety of new 
spectroscopic and computational methods. For all the ESRs,personalized 
training in advanced techniques will be combined with a broad common 
interdisciplinary background on dynamical processes in bio-macromolecules.
The consortium brings together 10 leading academic groups with
multidisciplinary expertise (chemistry, physics, biology) and a unique 
blend of experimental and computational skills. 
6 innovative companies, from SMEs specialized in click-chemistry 
and in biosensors to a pharma industry, will be fully integrated into 
the research and training programme and help promote the technological 
exploitation of its results.
LightDyNAmics will develop innovative molecular probes for DNA/protein 
interaction, paving the way to new diagnostic tools and new drugs. 
Partners: 
Consiglio Nazionale delle Ricerche, Istituto di Biostrutture  Bioimmagini(IT),
Centre National de la Recherche Scientifique, Lasers, Interactions and 
Dynamics Laboratory (FR), University of Durham (UK), Kemijski Intitut(SI),
Ludwig-Maximilians-Universitt Mnchen (DE), Masarykova Univerzita (CZ),
Politecnico di Milano (IT), University College Dublin (IE), Universit di 
Bologna (IT), Universitt Wien (AT), AstraZeneca Ltd (UK), Baseclick GmbH(DE),
Dynamic Biosensors GmbH (DE)

For further information about:
CEITEC, please visit 
http://www.ceitec.eu 
CEITEC Welcome Office, please visit 
http://www.ceitec.eu/ceitec-welcome-office/t1137 
Masaryk University, please visit 
http://www.muni.cz 
Brno, please visit 
http://www2.brno.cz/index.php?lan=en&nav01=20608&nav02=20617
Anticipated start date: September 2018

To apply, please contact Olga Krizova and email your resume/CV 
and a cover letter on phd|a|ceitec.muni.cz as soon as possible. 
Applicants will be considered until the position is filled.
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