|CCL 19.01.23 Computational Drug Hunter, Orion Corporation, Espoo, Finland|
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To: jobs at ccl.net
Date: Wed Jan 23 06:17:43 2019
Subject: 19.01.23 Computational Drug Hunter, Orion Corporation, Espoo, Finland
Orion is a globally operating Finnish company listed on the Helsinki Stock Exchange. Orion develops, manufactures and markets human and veterinary pharmaceuticals and active pharmaceutical ingredients for global markets. Orion's pharmaceutical innovations are created within its R&D organization, including e.g. non-clinical research, clinical development, formulation development and medical affairs. The organization employs top professionals in the field of drug molecule development and optimization. Global Medicine Design contributes to the drug discovery process of Orion R&D from target validation all the way to the candidate nomination. We are responsible for translating new drug targets to the small molecule therapeutics together with other line functions. Our scientists in biology, chemistry and computer-aided medicine design are key players in the multiple research programs driven by Orion's three therapy areas; CNS, Oncology and Rare Diseases. We also support biologics discovery with our core competences. Description of position: In order to maintain and enhance our capabilities we are now searching for a new enthusiastic Drug Hunter to join our Computer Aided Medicine Design team. The Computational Drug Hunter will work in our drug discovery R&D projects applying various computational tools and develop computer-aided drug design methods and processes. This includes both ligand- and structure-based design, protein modelling, structure-activity data analysis and knowledge extraction from a variety of in-house and public sources of experimental & computational data and literature. The Drug Hunter will collaborate closely with a broad range of scientists including other modellers, medicinal chemists, pharmacologists and biologists. The position is full-time and you will be based in Espoo, Finland. We offer: We offer you great, highly professional & experienced colleagues and the opportunity to show your talent and challenge yourself with interesting tasks in a modern multidisciplinary environment. Orion as the #1 research-based pharma company in Finland provides plenty of possibilities for personal development to become a true pharmaceutical industry expert. Generous health and welfare benefits are available, as well as support for international relocation. Requirements: - Ph.D. from a suitable field, e.g. computational chemistry, bioorganic chemistry, biophysics - Two years of post-doctoral or industrial experience relevant for drug discovery is appreciated - Experience in computational structure design, knowledge of state-of-the-art ligand- and structure-based methods and their applications for medicine design - Good general understanding of the drug discovery process (e.g. medicinal chemistry, pharmacology, cell biology) - In-depth experience in at least one of the following fields: Physics-Based methods (modelling and/or experimental) for medicine design, Application of Deep learning for Drug Discovery, Protein / Antibody Modelling, Molecular Dynamics simulations of biomolecules Experience with modelling software (preferably Schrdinger), data pipelining tools (e.g. Knime) andprogramming/scripting/data analysis/data visualization (e.g. Python/R) is desirable. For additional information about the position, please contact Julius Sipila, Head of Computer Aided Medicine Design, tel +358 50 966 2605 during the following times: - Wednesday, January 30 at klo 13-17 (UTC+2) - Wednesday, February 6 at 13-17 (UTC+2)
Please, send your application by February 12, 2019 through our webpage https://www.orion.fi/en/careers/open-vacancies?rmpage=job&rmjob=p258NOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED!!!
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