|CCL 19.02.05 PhD in Computational Biophysics, Brno, Czech Republic, EU|
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To: jobs at ccl.net
Date: Tue Feb 5 08:58:50 2019
Subject: 19.02.05 PhD in Computational Biophysics, Brno, Czech Republic, EU
Project: The project is focused on the regulation of protein interactions in genome transcription, which malfunction has been associated with numerous diseases including cancer. Despite the importance, we still lack the molecular understanding of how the involved posttranslational modifications and changes in salt and protein concentrations regulate the protein-protein interactions and the transcription. Expected findings are not only important for the general knowledge but could also be useful in the design of new treatments. The research is strongly coupled to collaborations with excellent experimental teams and will be more closely discussed during the interview. The student will master the tools of multiscale simulations using a wide range of techniques ranging from atomistic to coarse-grained simulations. Moreover, he/she will learn the advantages and disadvantages of various protein parameterizations, and advanced sampling techniques. Eligibility: Outstanding candidates with experience in computer simulations and with an MSc degree in the fields of biophysics, soft matter physics, physical chemistry, computational chemistry, statistical mechanics, or related fields. Experience with molecular dynamics simulations (with GROMACS, CHARMM, NAMD, AMBER, LAMMPS, etc.) or other simulation techniques (Monte Carlo, DPD, etc.) at the atomistic or coarse-grained level would be an advantage. Computing Resources: Successful candidates will have access to local computing clusters with 1500 cores. Access to Metacentrum NGI National Grid Infrastructure for computing (with ~15,000 cores) will be also available. Additional resources include the possibility of applying for IT4Inovations, where the group is active. Competitive salary supported by grant projects.
Applications must include a CV, motivation letter (description of research interests), and the names of 2 people willing to provide a letter of recommendation. Applications with all this material (preferably in a single pdf) should be sent to Robert Vacha (robert.vacha[#]mail.muni.cz).NOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED!!!
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