Investigator/Senior Investigator Free Energy Perturbation and Programming, Silicon Therapeutics, Boston, USA

Silicon Therapeutics, a Boston-based integrated computational drug discovery company, is looking for a computational scientist with expertise in developing molecular dynamics and free energy methods for drug discovery applications. Our science, our team, and our mission are focused on applying advanced computational technologies to build and progress a pipeline of innovative medicines for patients. We recently finalized our series A financing and are building a team of outstanding individuals to continue developing our computational platform. Competitive pay, equity, strong perks, and a fun working environment, along with desire to do cutting edge science to design better medicines, are all good reasons to join us! Learn more at www.silicontx.com . Email us at hr^^^silicontx.com with your resume and contact info. Please find the job description below:

Responsibilities:

• Implement robust, scalable solutions for alchemical free energy calculations
• Implement physics based workflows and novel methods to impact our drug discovery projects

Required Qualifications:

• Hihly motivated to develop physics-based free energy methods for discovering better medicines
• Ph.D. in computational chemistry, physical chemistry, chemical physics, or related fields
• Significant experience developing MD-based free energy methods and working with MD code
• Extensive programming experience (Python and C/C++ preferred)
• Advanced knowledge of scientific algorithm development
• Broad experience with statistical mechanics and thermodynamics
• Peer-reviewed publications in relevant areas and/or demonstrated success in related development projects

Additional Desirable Qualifications:

• Experience with structure-based drug design methods
• Experience with parallel programming (e.g. MPI, OpenMP, CUDA)

About Silicon Therapeutics
Silicon Therapeutics is an integrated computational drug discovery company focused on developing novel medicines for diseases with targets that are currently considered to be challenging for traditional approaches. Our INSITE platform closely represents the real dynamical nature of targets using accurate all-atom simulations, enabling us to design and optimize compounds for targets that were previously considered "undruggable." Our science, our team, and our mission are focused on applying advanced computational technologies to build and progress a pipeline of innovative medicines for patients. Silicon Therapeutics is headquartered in Boston, MA, USA with offices in Shanghai, China. Learn more at www.silicontx.com