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Date: Tue Feb 12 04:50:10 2019
Subject: 19.02.12 Postdoc in Computational Biochemistry
As a member of the Helmholtz Association, Forschungszentrum Jlich makes an effective
contribution to solving major challenges facing society in the fields of information, energy, and bioeconomy. It
focuses on varied tasks in the area of research management and utilizes large, often unique, scientific
infrastructure. Come and work with around 5,900 colleagues across a range of topics and
disciplines at one of Europes largest research centres.

The function of each cell and organism depends crucially on the dynamic interactions between biological macromolecules 
and their correct three-dimensional structure. Faulty interactions and misfolded structures ultimately lead to disease and aging. 
The goal of ICS-6 is to understand these interactions and to determine the three-dimensional structures of the protein complexes 
involved in crucial cellular processes as far as possible at atomic resolution. In addition, the department is developing novel methods 
for the early detection and therapy of neurodegenerative diseases with a strong focus on Alzheimers dementia.

We are looking to recruit a

Postdoc in Computational Biochemistry

Your Job:

The Computational Biochemistry Group, which is headed by Prof. Birgit Strodel, is part of the ICS-6 and focuses on the development
and application of computational methods for studying protein aggregation. The research topic of the project deals with the further 
development of a hybrid all-atom/coarse-grained simulation approach for studying Alzheimers amyloid- peptide in complex biological environments. 
This will allow unexpected new insight into the aggregation of amyloid- under near-native conditions. Tasks:

- Further development of a hybrid all-atom/coarse-grained model for amyloid peptides.
- Implementation of the resulting model into Gromacs.
- Application of the resulting model to simulate amyloid aggregation in complex environments.
- Cooperation with experimentalists to validate and address resulting findings.

Your Profile:

- A strong PhD degree in computational/theoretical biochemistry/biophysics or related
- Expert knowledge in the simulation of proteins at the atomistic and/or coarse-grained level using GROMACS or similar software
- Experience in method development, in particular in force field development
- Strong programming and scriptng skills (e.g., Python, C/C++, bash)
- Profound spoken and written English skills 
- Being creative, ambitious, highly motivated 
- Ability to work independently

Our Offer:

- Exciting working environment on an attractive research campus with excellent infrastructure, located between the cities of Cologne, Dsseldorf, and Aachen
- International and interdisciplinary working atmosphere
- A comprehensive further training programme
- Flexible working hours and various opportunities to reconcile work and private life
- Limited for 2 years with possible longer-term prospects
- Full-time position with the option of slightly reduced working hours
- Salary and social benefits in conformity with the provisions of the Collective Agreement for the Civil Service (TVD). 
Depending on the applicant's qualifications and the precise nature of the tasks, salary grade 13 TVD-Bund

Forschungszentrum Jlich aims to employ more women in this area and therefore particularly welcomes applications from women.

We also welcome applications from disabled persons.
We look forward to receiving your application until 10.03.2019 via our Online-RecruitmentSystem!

Questions about the vacancy?

Contact us by mentioning the reference number 2019-042:

Please note that for technical reasons we cannot accept applications via email.
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Please let your prospective employer know that you learned about the job from the Computational Chemistry List Job Listing at If you are not interested in this particular position yourself, pass it to someone who might be -- some day they may return the favor.
Modified: Tue Feb 12 09:50:10 2019 GMT
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