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Date: Tue Oct 15 14:57:05 2019
Subject: 19.10.15 Scientist, Computational Chemistry: Cambridge, MA Biotech delivering on the promise of mRNA Science
Title:		Scientist, Computational Chemistry
Location:	Cambridge, MA
Reports to:	Principal Scientist, Computational Chemistry

The Role:
Moderna is seeking a modeler with a background in coarse-grained molecular dynamics simulations to tackle challenging problems in drug product delivery and efficacy. This person will be responsible for in silico characterization and prediction of our lipid nanoparticles for drug delivery. He/she will work closely with our drug delivery group to understand mechanism of action for delivery and optimize for efficacy. This position reports to the Principal Scientist in Computational Chemistry.

Heres What Youll Do: 
 Characterize novel lipid nanoparticles (LNPs) structures using state of the art coarse-grained molecular dynamics simulations
 Correlate predicted LNP structure to function and efficacy of drug product
 Discover new computational methodology, create workflows and share successful methods
 Drive the development of next generation drug delivery vehicles, including LNPs and polymers
 Setup, install, and maintain all necessary software packages to perform coarse-grained simulations, e.g., MARTINI and GROMACS
 Collaborate with groups across the company to support research projects, including Delivery Science, Chemistry and Technical Development
 Apply chemistry, physics, and engineering knowledge to draw rigorous, actionable conclusions from complex data 
 Communicate findings internally and externally

Heres What Youll Bring to the Table:
 Ph.D. and 0-2 years of experience in physical chemistry, chemical engineering, biophysics, bioengineering or related field
 Extensive experience in coarse-grained molecular dynamics simulations, preferably of lipids
 Proficient in at least one programming or scripting language, such as Python or Perl
 Comfort working in a Linux-based High Performance Computing environment
 Willingness to learn and tackle abstract problems
 Comfortable operating in a rapidly-changing environment and making actionable conclusions from incomplete data
 Creative problem solver able to draw conclusions from complex datasets, and present them in a clear and understandable way
 Strong written and oral communication skills

Heres What Well Bring to the Table:
 Daily on-site catered lunches
 Company-provided iPhone
 Free parking, monthly subway pass or a subsidized commuter rail pass
 Free annual corporate membership to Bluebikes
 Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
 Flexible Spending Accounts for medical expenses and dependent care expenses
 16 weeks of 100% paid parental leave for all new parents 
 16 weeks 100% paid family caregiver leave
 20 weeks 100% paid medical leave
 Adoption assistance and discounts to local childcare centers, as well as access to
 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
 A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
 Voluntary legal assistance plan
 15 days vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays (includes 2 floating holidays)

Why join Moderna 
At Moderna, we believe messenger RNA, or mRNA, is the software of life. Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease. Given its essential role, we believe mRNA could be used to create a new category of medicines with significant potential to improve the lives of patients.

Headquartered in Cambridge, Mass., Moderna currently has strategic alliances for development programs with AstraZeneca, Plc. and Merck, Inc., as well as the Defense Advanced Research Projects Agency (DARPA), an agency of the U.S. Department of Defense; and the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS). Moderna has been ranked in the top ten of Sciences list of top biopharma industry employers for the past four years. To learn more, visit

Our Mission:
Deliver on the promise of mRNA science to create a new generation of transformative medicines for patients.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Please apply directly on our Careers page:
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Modified: Mon Oct 21 17:57:49 2019 GMT
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