|CCL 19.10.22 PhD Position in Theoretical and Computational Membrane Biophysics, Erlangen, Germany|
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Date: Tue Oct 22 06:48:25 2019
Subject: 19.10.22 PhD Position in Theoretical and Computational Membrane Biophysics, Erlangen, Germany
PhD Positions in Theoretical and Computational Membrane Biophysics at Friedrich-Alexander University of Erlangen-Nuremberg, Germany Applications are invited for PhD positions in theoretical and computational membrane biophysics in the Computational Biology Group of Rainer Boeckmann at the University of Erlangen-Nuremberg, Germany. Projects Plasma membranes and in general biomembranes establish and maintain differences in composition between the cell or organelle interior and exterior. Biomembranes are the site for cell-cell recognition, they allow active and passive transport of material into and out of the cell, and they harbour proteins as initiators of signal transduction pathways. Projects within the international group focus on lipid-protein interaction, membrane dynamics, membrane phase transition, structure-dynamics-function relationship of membrane channels using methods from statistical and computational physics, i.e. atomistic and coarse-grained molecular dynamics simulations. The aim is to shed light on the cooperative action of proteins and lipids in shaping biomembrane structure and their contribution to micro-scale compartmentalization. Possible PhD Projects: (1) The doctoral researcher will study the role of peptide-lipid interactions in membrane fusion. Central questions are: How to peptides induce membrane curvature, what is the role of lipid composition and peptide oligomerization in synaptic vesicle fusion? Which molecular mechanisms are involved in spatial control and assembly? (2) This project focuses on the mechanical properties of biomembrane mimetics and the domain-dependent sorting of membrane proteins. The aim is to decipher the driving forces involved in sorting, signal transduction and transport through biological membranes. Requirement Candidates should preferably hold a master in bio-/physics, theoretical/computational chemistry, or similar, have a good knowledge of statistical mechanics, programming skills and a strong interest in interdisciplinary projects. Other requirements High level of English and good communication skills; effective team working. We offer 3 years PhD contract and a competitive salary (65% E13). Interested candidates should send one pdf document containing a cover letter, CV, and certificates to rainer.boeckmann(_)fau.de. For further information please visit www.biomemphys.nat.fau.de About Erlangen: The University of Erlangen-Nuemberg (FAU) was founded in 1743 and currently has about 37,000 students.The Faculty of Sciences is located in Erlangen, a city with a historic baroque centre which is located amidst a splendid landscape close to the rocky hills and lovely forests of the Fraenkische Schweiz. The cities of Nuremberg (a traditional centre of arts and commerce since medieval times) and Bamberg (a UNESCO world heritage town) lie about 20 km to the south and 40 km to the north, respectively. Bayreuth(renowned for the world-famous opera composer Richard Wagner and the according festival) is about 80 km away, while Munich, Frankfurt and Stuttgart, the other large cities of southern Germany, can all be reached within about 2 hours journey by train or car. One of Erlangens best known and most loved attractions is the Bergkirchweih, a beer festival in spring, which attracts around 1 million visitors from near and far. For more extracurricular activities in and around Erlangen see link to main webpage of FAU. In the wider world, Erlangen is also renowned both as home to the second largest university in Bavaria and as one of the three headquarters of Siemens AG which both contribute substantially to the high living standard in and around the city. With its broad range of additional privately and publicly funded research facilities and many start-up high-tech companies Erlangen and its surroundings have developed into an important European R&D centre in several future-oriented areas of engineering, including medical systems, microelectronics, audio (Fraunhofer IIS, Dolby), multimedia and communications (e.g. Intel Comneon, Alcatel-Lucent).NOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED!!!
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