|CCL 21.01.08 Senior/Principal Molecular Modeler, Galapagos nv, Romainville, FR|
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To: jobs at ccl.net
Date: Fri Jan 8 05:59:16 2021
Subject: 21.01.08 Senior/Principal Molecular Modeler, Galapagos nv, Romainville, FR
Pleased to meet you, we are Galapagos, a dynamic fast growing Biotech company with offices in Europe in Belgium (Mechelen), France (Romainville & Paris), the Netherlands (Leiden), Switzerland (Basel), Italy (Milano), Spain (Madrid), the UK (London), Germany (Mnchen), and in the US(Boston) Were in the business of changing lives. In our quest to discover and develop life-improving medicines we go where no one has ever gone before. In every challenge we face, we see new opportunities. We want to challenge the impossible. We need thought leaders and rapid thinkers, entrepreneurs in spirit and status quo-fighters. Collaborative innovators and perseverant idealists. We need the best-in-class. In other words, we need you. We are looking for a Senior/Principal Molecular Modeler - Romainville,FR Scope of the job As member of the Molecular Modelling & Design team (part of the Computational Research group, 10 people), your primary responsibility will be the judicious application of computational methods to the discovery and optimization of drug candidates. You will be involved in structure-based (SB) and ligand-based (LB) drug design, compound selection and acquisition, HTS data analysis and triage ,virtual screening, statistical modelling, and ADMET prediction. You will be working closely with medicinal chemists, biologists, DMPK scientists and other project team members to define and achieve project goals. You will also have the opportunity to participate in evaluating, developing, implementing and applying new computational methodologies and strategies. You will identify areas of scientific improvement within computational sciences and their potential for application to projects. You will contribute to the development of new computational capabilities and maintain an up to date awareness of recent literature and current developments within the field. Who are you? -A Ph.D. degree followed by at least 3 years of experience in computer-aided support to drug discovery projects in a multi-disciplinary project team. Experience in an industrial setting would be an advantage. -Expertise in structure- and ligand-based drug design, with strong experience in common molecular modelling techniques (protein homology modelling, docking, pharmacophore modelling, target- and ligand-based virtual screening) -Strong expertise in at least one of the following techniques: ADMET and physicochemical property prediction, machine learning, molecular simulations (MD), FEP, quantum mechanics calculations -A good background in organic chemistry and a solid knowledge of medicinal chemistry concepts -Additional required skills: Experience with data-workflow tools (such as Pipeline Pilot or Knime) Programming, scripting (Python) Good knowledge of Linux and awareness of the latest hardware and cloud solutions Knowledge of drug target families (kinases, GPCRs, proteases, PDEs) Experience with databases and querying languages (such as SQL) would be a plus Whats in it for you? You will be part of a fast growing and amazing company. As make-it-happener you will get all the support you need to make your job successful. At Galapagos we aim to recruit the best people, who stand out among their peers, with integrity and excellent interpersonal and organizational skills. Our employees are the strength behind Galapagos, a highly motivated team, eager to maintain Galapagos leading position and achieve breakthroughs in pharmaceutical research. Galapagos offers a competitive remuneration package and a dynamic work environment. We are Galapagos : together we can make it happen!
You can show your interest by sharing your application with Wim Vanhaele, Talent Acquisition Lead Research - wim.vanhaele**glpg.com. Looking forward to speaking with you.NOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED!!!
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