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Up Directory CCL 21.05.12 Technical Expert Computational Chemistry, Syngenta, Bracknell, UK
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Date: Wed May 12 12:22:45 2021
Subject: 21.05.12 Technical Expert Computational Chemistry, Syngenta, Bracknell, UK

Technical Expert Computational Chemistry, Syngenta, Bracknell, UK

Location: Bracknell, United Kingdom
Employment Type: Permanent
Job Function: Research & Development (R&D)
Job Reference: 18028780
Contract Type: Full-time

About Syngenta:
Syngenta is a leading agriculture company helping to improve global food security by enabling millions of farmers to make better use of available resources more sustainably. Through world class science and innovative crop solutions, our 28,000 people in over 90 countries are working to transform how crops are grown. We are committed to rescuing land from degradation, enhancing biodiversity and revitalizing rural communities.

About this job:
We are looking for a highly motivated computational chemist to join the Computational Chemistry group at our R&D site in Jealott's Hill, UK. The role offers an exciting opportunity to work on chemistry design problems in a multidisciplinary environment, with applications in a wide range of biological systems spanning plant, mammalian and invertebrate biology.

The successful candidate will need to demonstrate flexible teamwork and a tenacious approach to delivering computational chemistry outputs to research projects. Excellent oral and written communication skills and the ability to translate specialist knowledge into a meaningful output for multidisciplinary project teams are highly desirable qualities for this position.

Accountabilities:

  • Support design of new active ingredients by using a broad range of computational techniques, including data analysis and predictive modelling; molecular modelling, structure- and ligand-based designWork with chemists, computational chemists, biologists and other experts to devise strategies on how best to leverage data and provide design inputs to support chemical invention
  • Build project structure-property relationships, analyse biological data and help project teams to make decisions and drive hypothesis-based molecular design
  • Understand business context and monitor new developments in the field of computational chemistry
  • Work effectively with computational chemistry colleagues across R&D to drive technology development and promote the use of state-of-the-art methods

Required knowledge and experience:

  • PhD or equivalent in computational chemistry or a related field, with experience in project-based work in multidisciplinary project teams
  • Working knowledge of cheminformatics, QSPR, model validation and assessing model robustness; familiarity with machine learning and its applications
  • Knowledge of ligand-based rational design, e.g. field- and shape-based methods and conformational exploration, standard QM methods
  • Knowledge of structure-based design, including homology modelling, docking and virtual screening
  • Understanding of organic chemistry and chemical structure
  • Familiarity with standard molecular modelling software packages
  • Practical programming and data science skills to support computational chemistry tasks, e.g. Python, shell scripting, high-performance computing, pipelining tools, databases
  • Experience in an industrial drug discovery environment is a plus

Syngenta will offer:

  • Competitive benefits package
  • Up to 31.5 days holiday
  • An opportunity to work in a talented, high performing team

Please direct informal questions about the position to daniel.kloer-$-syngenta.com, but if you wish to apply, you must do this via the Syngenta Careers website at the link: https://www.syngenta.com/en/job/en/18028780/external?dlang=264

We embrace and encourage diversity, and this is what drives our innovation and lets us outperform the market. https://www.syngenta.com/careers/working-syngenta/diversity-and-inclusion



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