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Up Directory CCL 21.05.25 Team Leader Computational Chemistry, Galapagos nv, Mechelen, Belgium
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Date: Tue May 25 03:56:19 2021
Subject: 21.05.25 Team Leader Computational Chemistry, Galapagos nv, Mechelen, Belgium
Pleased to meet you, we are Galapagos, a dynamic fast growing Biotech 
company with offices in Europe in Belgium (Mechelen), France
(Romainville and Paris), the Netherlands (Leiden), Basel (Switzerland), 
Spain (Madrid), Italy (Milan) and in the US, (Boston).

Were in the business of changing lives. In our quest to discover and 
develop life-improving medicines we go where no one has ever gone before. 
In every challenge we face, we see new opportunities. We want to 
challenge the impossible. We need thought leaders and rapid thinkers, 
entrepreneurs in spirit and status quo-fighters. Collaborative innovators
and perseverant  idealists. We need the best-in-class. In other words, we
need you : The make-it-happeners.


We are looking for a Team Leader Computational Chemistry  - Mechelen,BE 
or Romainville, FR


As Team Leader for the "Molecular Modelling & Design" team, you will be 
responsible for the judicious application of computational methods to the
discovery and optimization of drug candidates. You will provide 
scientific contributions to drug discovery projects yourself and 
supervise 3 other team members in this endeavor.

You will be involved in structure-based (SB) and ligand-based (LB) drug 
design, compound selection and acquisition, HTS data analysis and triage,
virtual screening, statistical modelling, and ADMET prediction. You will 
be working closely with medicinal chemists, biologists, DMPK scientists 
and other project team members to define and achieve project goals.

As part of the larger Computational Research group (10 people), you will 
also have the opportunity to participate in evaluating, developing, 
implementing and applying new computational methodologies and strategies. 
You will identify areas of scientific improvement within computational 
sciences and their potential for application to projects. You will 
contribute to the development of new computational capabilities and 
maintain an up-to-date awareness of recent literature and current 
developments within the field.

You will be located either on the Mechelen (Belgium, Brussels area) or 
Romainville (France, Paris area) site, to your convenience.

Who are you?

-A Ph.D. degree with a demonstrated track record in computer-aided 
support to drug discovery projects. Experience in an industrial setting 
would be an advantage.
-Expertise in structure- and ligand-based drug design, with strong 
experience in common molecular modelling techniques (protein homology 
modelling, docking, pharmacophore modelling, target- and ligand-based 
virtual screening)
-Expertise in at least one of the following techniques would be a plus: 
ADMET and physicochemical property prediction, machine learning, 
molecular simulations (MD), FEP, quantum mechanics calculations
-A good background in organic chemistry
-Programming, scripting (Python), and good knowledge of Linux
-Experience with data-workflow tools (such as Pipeline Pilot or Knime)
-Knowledge of drug target families (kinases, GPCRs, proteases, PDEs)
-Experience in managing teams in an international context
-Fluent in English, preferably also in Dutch and/or French
You will be part of a fast growing and amazing company. As a 
make-it-happener you will get all the support you need to make your job
successful. At Galapagos we aim to recruit the best people, who stand out
among their peers, with integrity and excellent interpersonal and 
organizational skills. Our employees are the strength behind Galapagos, 
a highly motivated team, eager to maintain Galapagos leading position 
and achieve breakthroughs in pharmaceutical research. Galapagos offers a 
competitive remuneration package and a dynamic work environment.


We are Galapagos: together we can make it happen...!
Please send your cv to wim.vanhaele*
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Modified: Tue May 25 07:56:19 2021 GMT
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