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Date: Thu Jun 3 04:31:46 2021
Subject: 21.06.03 Computational Chemist PhD at leading chemistry and drug discovery CRO in Europe, Netherlands
Symeres is one of the leading chemistry and drug discovery Contract Research Organizations (CROs) in Europe, with over 500 scientists at six locations (Nijmegen, Weert and Groningen in the Netherlands, Prague in the Czech Republic,
Oulu in Finland, and Sodertalje in Sweden). We provide a range of services to support small-molecule drug discovery and development projects for biopharmaceutical companies worldwide. We have medicinal chemistry teams in both our 
Nijmegen and Groningen locations (previously called Mercachem and Syncom), currently totaling about 80 scientists. To grow the computational team in Nijmegen, we are currently looking for a skilled and enthusiastic

Computational Chemist
Drug Discovery Full time

In this position, you will be involved in drug discovery projects on different target classes and disease areas supporting both the Nijmegen and Groningen teams. You will apply computational methods, including structure-based 
drug design, homology modeling, QSAR, ligand/receptor docking, ligand-based design, scaffold hopping and diversity/similarity analysis, in the design of libraries or single compounds. Furthermore, you will interpret and use 
structural data, biological assay data, physicochemical data, pharmacological data etc in the design of biological active molecules. Your key interactions are with medicinal chemists on the customer side, and with 
medicinal/synthetic chemists internally. 

For this position, we are looking for an enthusiastic, pleasant person who meets the following criteria:

Required experience
 	PhD in computational chemistry or related discipline
 	Hands-on experience with ligand- and/or structure-based design
 	Profound knowledge of computational and medicinal chemistry concepts
 	Basic knowledge of synthetic organic chemistry

Desired experience
 	Post-doctoral work as a computational chemist in drug discovery, preferably in an industrial environment
 	The ability to program, e.g. in Python and/or experience with KNIME
 	Designing and handling (large) molecular libraries
 	Knowledge of statistical methods
 	Progressing compounds from hit through lead to clinical candidate

 	Enthusiasm for and interest in all methodological and technological aspects related to Medicinal and Computational Chemistry
 	Hard working, creative, flexible, confident, and reliable 
 	Excellent verbal and written communication skills
 	Customer and service oriented

Job Offer
An exciting position in a dynamic organization with an attractive remuneration package and opportunities for learning and development.

Are you interested in this position? And do you meet the job requirements? Please send an email with your CV and motivation letter to our HR manager, Thea Scherpenborg, by email: hrm.hrm{=} For substantive questions, 
please contact Anita Wegert (Director MedChem) at telephone number: +31243723300. More information about the Symeres organization can be found on our website:  

This vacancy is open for EU residents only.

Acquisition based on this advertisement is not appreciated

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