From: jobs at (do not send your application there!!!)
To: jobs at
Date: Mon Jul 26 09:48:23 2021
Subject: 21.07.26 Computational Scientist, Infectious Disease Research at Moderna - Hiring Now!
Moderna is hiring in Cambridge, MA! Come help us deliver on the promise of 
mRNA science to create a new generation of transformative medicines for 

The Role:
Moderna's Infectious Disease Research group is seeking a talented, 
experienced and motivated Bioinformatician Scientist to be part of the 
vaccine discovery team for a wide range of disease targets. The 
Scientist will apply expertise in structural bioinformatics and 
immunology to design novel mRNA sequences for candidate vaccines. 
The Scientist will work with other members of the Infectious disease 
team and external collaborators on the discovery and development of 
Modernas mRNA vaccine and immunotherapy candidates and help to 
advance these into IND-enabling studies. The Scientist will collaborate 
with other cross-functional teams to evaluate designed mRNAs in the lab 
and present results internally and externally. The role will involve 
collaboration with other scientists within the Moderna ecosystem including, 
among others, cellular immunologists, virologists, bacteriologist and 
computational scientists to design novel vaccine candidates against 
infectious disease targets. Located in Cambridge, MA, the Scientist 
should be outstanding in their fields, collaborative team members and 
excellent communicators.

Here's What You'll Do: 
Bioinformatically analyze protein structures and sequences from pathogens
and design mRNA vaccine sequences for testing in vitro by other team 
Propose novel vaccine and therapeutic targets aligned with Modernas 
scientific strategy and capabilities. Interpret, troubleshoot, and report 
complex data.
Align with Infectious Disease Research group members for key antigen 
design needs and the evaluation of the designed mRNA vaccine candidates.
Work closely with cross-functional teams across the Moderna ecosystem, 
collaborators and CROs to progress candidates from discovery through 
IND-enabling studies.
Maintain expertise in the field of infectious disease, immunotherapy and 
therapeutic developments, biomarker discovery and patient outcomes, attend 
conferences, and liaise with external experts in the field.
Manage multiple experiments, projects and interactions with supporting 
Apply scientific expertise to identify mRNA vaccine and immunotherapy 
discovery strategies.
Provide scientific and technical support to interdisciplinary project 
Prepare documents and present strategy, results, project updates, 
and summaries. 

Here's What You'll Bring to the Table:
Exceptional PhD in Bioinformatics, Computational Biology, Computer 
Science, or related field. 
Experience in protein redesign, homology modeling, and sequence analyses 
is required. We are particularly interested in candidates with prior 
experience in structure-based vaccine design.
Experience in either free energy calculation or molecular dynamics is 
Proficiency in Unix-based systems, scripting language (Python/R/Perl), 
a good working knowledge of relevant data analysis and visualization 
packages including 3D protein structure.
Experience in T-cell and B-cell epitope prediction is a plus.
Experience in sequence-feature analysis is a plus.
Proven ability to interpret complex data and present conclusions 
in a clear and understandable way to a broad audience.
Strong written and oral communication skills, comfort with senior 
management interactions 
Strong time management and problem-solving skills.
Positive team building and teamwork skills, willing to give and 
receive constructive feedback
Proven track record of high impact publications and presentations 
in the field of protein or antigen design.
The Ability to work in a cross-functional work environment is critical, 
engagement with personnel in different parts of the company; strong 
leadership skills and independence are expected.
Excellent written, presentation and interpersonal communication skills; 
ability to influence and collaborate in a team environment.
Candidate will be curious in exploring new paths for vaccine and drug 
discovery, bold in proposing creative experimental designs and ideas. 
Will work collaboratively with multifunctional teams and will be 
relentless in pursuing successful outcomes.

Our benefits 
Here's What We'll Bring To The Table
On-site subsidized cafeteria or catered lunches
Company-provided iPhone
Free parking, monthly subway pass or a subsidized commuter rail pass
Free annual corporate membership to Bluebikes
Highly competitive healthcare coverage including: medical offered through 
BCBS (HMO/PPO), dental, and vision offered through VSP
Flexible Spending Accounts for medical expenses and dependent care 
16 weeks of 100% paid parental leave for all new parents
16 weeks 100% paid family caregiver leave
20 weeks 100% paid medical leave
Eligible for Moderna Month (one month paid sabbatical after five years 
of service and eligible for additional one month paid sabbatical every 
3 years thereafter)
Adoption assistance and discounts to local childcare centers, as well as 
access to
401k (traditional and Roth offered) with 50% match on first 6% deferred. 
Match is vested immediately
A suite of Moderna paid insurance coverage, including: life insurance, 
short-term and long-term disability
Voluntary legal assistance plan
15 days vacation and 7 sick days per year, in addition to a 
discretionary winter shut down and 11 company 
paid holidays (includes 2 floating holidays)
Please apply via our website:

Req. 5249
All @ signs were changed to ]_[ to fight spam. Before you send e-mail, you need to change ]_[ to @
For example: change joe]_[ to
Please let your prospective employer know that you learned about the job from the Computational Chemistry List Job Listing at If you are not interested in this particular position yourself, pass it to someone who might be -- some day they may return the favor.