|CCL 21.08.03 Postdoctoral position in computational biophysics at the University of Notre Dame|
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Date: Tue Aug 3 15:04:15 2021
Subject: 21.08.03 Postdoctoral position in computational biophysics at the University of Notre Dame
A postdoctoral position in computational biophysics is available in the Wiest group at the University of Notre Dame. The position is fully funded for five years through a recent NIH R01 grant. The starting salary will follow NIH guidelines and is expected to be ~$52,000/year plus generous benefits and professional development opportunities. The University of Notre Dame is located in South Bend, IN, an area with reasonable cost of living 90 minutes southeast of Chicago. Excellent computational resources, including large CPU and GPU clusters, are available for the project. The goal of the project is to elucidate the oligomerization of VP40, a protein that is essential for many filoviruses including ebola and Marburg viruses. The goal of the project is to understand the effect of mutations on the oligomerization and the design of stapled peptide helices as chemical probes. This project is a collaboration of the Wiest group with the Stahelin group at Purdue University and the DelValle group at the University of Notre Dame. It interfaces with the computer aided molecular design facility in the Warren Center for Drug Discovery, which offers the opportunity to gain additional experience in computational drug design. Position Requirements: - PhD in chemistry, biochemistry, biophysics or related field - Demonstrated experience with molecular dynamics simulations of proteins and other biomolecules - Demonstrated ability to work in a multidisciplinary team that include experimental chemists and biophysicists - Ability of handle multiple projects simultaneously - Excellent verbal and written communication skills. Experience with other aspects of computer aided drug design such as python scripting, advanced sampling methods, study of protein-protein interactions, docking, model building and validation, electronic structure calculations, free energy perturbation and force field parameterization are beneficial. The Wiest group is committed to a diverse and supportive environment and encourages applications from a range of backgrounds. Applicants should submit a cover letter explaining their interests in and specific qualifications for the position, a CV, and a list of three writers of letters of recommendation to camd(at)nd(dot)edu.NOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED!!!
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