D. E. Shaw Research is seeking computational and theoretical chemical physicists, as well as 
applied mathematicians and other computational scientists with a background in theory and a 
track record of achievement, to join our New Yorkbased team.  This is a unique opportunity to 
develop and work with transformative technology in a dynamic, interdisciplinary environment.  

Relevant areas of experience might include the development of methods for molecular dynamics 
simulations, such as integrators or efficient approximations of long-range forces, methods for 
enhanced sampling or free-energy calculations, or machine learning approaches for analyzing 
large data sets.  Specific knowledge of any of these areas is less critical, however, than 
strong research skills, and a history of innovation and accomplishment.  

We are committed to fostering a stimulating, rewarding, and flexible work environment, and 
we offer above-market compensation.  We also provide generous relocation and immigration 
assistance to new hires.  In addition, we strive to support the personal and professional 
needs of our team members by offering generous benefits, opportunities for community engagement, 
and a variety of learning and development programs.  

To submit an application, please use the link provided below: 

https://deshawresearch.avature.net/careers/Register?pipelineId=568&source=CCL.net+-+M

D. E. Shaw Research (DESRES) is a New York-based drug discovery and computational biochemistry 
research company developing and using advanced computational technologies to understand the 
behavior of biologically and pharmaceutically significant molecules at an atomic level of detail, 
and to design precisely targeted, highly selective drugs for the treatment of various diseases.  
Among our core technologies is a proprietary special-purpose supercomputer called ANTON which 
we designed and constructed to perform molecular dynamics simulations more than 100 times faster 
than the world's fastest general-purpose supercomputers.  DESRES develops and refines advanced 
biomolecular modeling methods, software, and machine learning techniques on ANTON, as well as 
on general-purpose supercomputers, in order to pursue both internal and collaborative drug 
discovery programs.

D. E. Shaw Research is an equal opportunity employer, dedicated to the goal of building a diverse 
workforce. We embrace diversity along all dimensions, and respect and value the unique qualities, 
perspectives, and identities of every person in our group. We welcome inquiries from all 
exceptionally well-qualified applicants, regardless of race, color, nationality, national or 
ethnic origin, religion or religious belief, caste, gender identity, pregnancy, caregiver status, 
age, military service eligibility, veteran status, sexual orientation, marital or civil partner 
status, disability, or status in any other category protected in this regard by law in any 
jurisdiction in which we operate. 

The expected annual base salary for this position is $300,000 - $450,000.  Our compensation 
package also includes variable compensation in the form of sign-on and year-end bonuses, and 
generous benefits.  The applicable annual base salary paid to a successful applicant will be 
determined based on multiple factors including the nature and extent of prior experience and 
educational background.

https://deshawresearch.avature.net/careers/Register?pipelineId=568&source=CCL.net+-+M