D. E. Shaw Research is seeking postdoctoral fellows to join our New Yorkbased team.  
This is a unique opportunity to develop and work with transformative technology in a 
dynamic, interdisciplinary environment.  Candidates should have expertise in computational, 
theoretical, or quantum chemistry, computational biophysics, structural biology, drug 
discovery, theoretical chemical physics, applied mathematics, or in a relevant area of 
computer science.

Relevant areas of experience might include direct application of molecular dynamics, 
machine learning, or other computational methods to drug discovery, investigation of 
allosteric interactions or other functionally important conformational changes in 
biological molecules, structure prediction or design for proteins or RNA, study of 
protein-protein or protein-nucleic acid interactions, force field improvement through 
detailed comparisons of simulation data with NMR measurements or other experimental 
data, development and implementation of new methodology, such as integrators or 
efficient approximations of long-range forces, methods for enhanced sampling or 
free-energy calculations, or tools to efficiently analyze large simulation datasets.  
Specific knowledge of any of these areas is less critical, however, than strong 
research skills, and a history of innovation and accomplishment. 

We are committed to fostering a stimulating, rewarding, and flexible work environment, 
and we offer above-market compensation.  We also provide generous relocation and 
immigration assistance to new hires.  In addition, we strive to support the personal 
and professional needs of our team members by offering generous benefits, opportunities 
for community engagement, and a variety of learning and development programs.  

To submit an application, please use the link provided below:  

https://deshawresearch.avature.net/careers/Register?pipelineId=580&source=CCL.net

D. E. Shaw Research (DESRES) is a New York-based drug discovery and computational 
biochemistry research company developing and using advanced computational technologies 
to understand the behavior of biologically and pharmaceutically significant molecules 
at an atomic level of detail, and to design precisely targeted, highly selective drugs 
for the treatment of various diseases.  Among our core technologies is a proprietary 
special-purpose supercomputer called ANTON which we designed and constructed to 
perform molecular dynamics simulations more than 100 times faster than the world's 
fastest general-purpose supercomputers.  DESRES develops and refines advanced 
biomolecular modeling methods, software, and machine learning techniques on ANTON, 
as well as on general-purpose supercomputers, in order to pursue both internal and 
collaborative drug discovery programs.

D. E. Shaw Research is an equal opportunity employer, dedicated to the goal of building 
a diverse workforce. We embrace diversity along all dimensions, and respect and value the 
unique qualities, perspectives, and identities of every person in our group. We welcome 
inquiries from all exceptionally well-qualified applicants, regardless of race, color, 
nationality, national or ethnic origin, religion or religious belief, caste, gender identity, 
pregnancy, caregiver status, age, military service eligibility, veteran status, sexual 
orientation, marital or civil partner status, disability, or status in any other category 
protected in this regard by law in any jurisdiction in which we operate. 

The expected annual base salary for this position is $220,000 - $240,000.  Our compensation 
package also includes variable compensation in the form of sign-on and year-end bonuses, 
and generous benefits.  The applicable annual base salary paid to a successful applicant 
will be determined based on multiple factors including the nature and extent of prior 
experience and educational background.

https://deshawresearch.avature.net/careers/Register?pipelineId=580&source=CCL.net