D. E. Shaw Research is seeking scientists with experience in computational drug discovery or 
related areas to join our New Yorkbased team.  This is a unique opportunity to develop and 
work with transformative technology in a dynamic, interdisciplinary environment.

Areas of expertise relevant to our molecular dynamicsbased drug discovery efforts include 
molecular modeling, machine learning, fragmentbased drug design, cheminformatics, and 
medicinal chemistry.  An ability to leverage experimental data to inform computational 
approaches would be a plus, as would knowledge of structural biology.  Specific knowledge 
of any of these areas is less critical, however, than strong research skills, and a record 
of impact in drug discovery.

A successful hire will directly contribute to projects within our expanding portfolio of 
drug discovery programs, which we pursue both independently and in collaboration with 
leaders in academia and industry.

We are committed to fostering a stimulating, rewarding, and flexible work environment, 
and we offer above-market compensation.  We also provide generous relocation and immigration 
assistance to new hires.  In addition, we strive to support the personal and professional 
needs of our team members by offering generous benefits, opportunities for community engagement, 
and a variety of learning and development programs.  

To submit an application, please use the link provided below: 

https://deshawresearch.avature.net/careers/Register?pipelineId=570&source=CCL.net

D. E. Shaw Research (DESRES) is a New York-based drug discovery and computational biochemistry 
research company developing and using advanced computational technologies to understand the 
behavior of biologically and pharmaceutically significant molecules at an atomic level of 
detail, and to design precisely targeted, highly selective drugs for the treatment of various 
diseases.  Among our core technologies is a proprietary special-purpose supercomputer called 
ANTON which we designed and constructed to perform molecular dynamics simulations more than 
100 times faster than the world's fastest general-purpose supercomputers.  DESRES develops and 
refines advanced biomolecular modeling methods, software, and machine learning techniques on ANTON, 
as well as on general-purpose supercomputers, in order to pursue both internal and collaborative 
drug discovery programs.

D. E. Shaw Research is an equal opportunity employer, dedicated to the goal of building a diverse 
workforce. We embrace diversity along all dimensions, and respect and value the unique qualities, 
perspectives, and identities of every person in our group. We welcome inquiries from all exceptionally 
well-qualified applicants, regardless of race, color, nationality, national or ethnic origin, religion 
or religious belief, caste, gender identity, pregnancy, caregiver status, age, military service 
eligibility, veteran status, sexual orientation, marital or civil partner status, disability, or 
status in any other category protected in this regard by law in any jurisdiction in which we operate. 

The expected annual base salary for this position is $300,000 - $450,000.  Our compensation package 
also includes variable compensation in the form of sign-on and year-end bonuses, and generous benefits.  
The applicable annual base salary paid to a successful applicant will be determined based on multiple 
factors including the nature and extent of prior experience and educational background.

https://deshawresearch.avature.net/careers/Register?pipelineId=570&source=CCL.net