D. E. Shaw Research is seeking pre-clinical translational scientists with experience in drug 
discovery to join our New Yorkbased team.  This is a high-visibility, high-impact role that 
affords the opportunity to help shape our drug discovery programs.  Responsibilities include 
working collaboratively with our team of computational scientists and consultants on target 
evaluation, selection, and translational strategy; overseeing experimental work at our CRO 
partners from the design and implementation of functional cell assays to in vivo testing; and 
providing strategic advice regarding new drug discovery opportunities across therapeutic areas.

Relevant areas of experience include leadership of pre-clinical drug discovery programs, 
design of in vitro assays as well as in vivo disease models, and formulation of translational 
plans.  Specific knowledge of any of these areas is less critical, however, than strong research 
and communication skills, and a record of impact in drug discovery.

A successful hire will directly contribute to projects within our expanding portfolio of drug 
discovery programs, which we pursue both independently and in collaboration with leaders in 
academia and industry.

We are committed to fostering a stimulating, rewarding, and flexible work environment, and we 
offer above-market compensation.  We also provide generous relocation and immigration assistance 
to new hires.  In addition, we strive to support the personal and professional needs of our team 
members by offering generous benefits, opportunities for community engagement, and a variety of 
learning and development programs.  

To submit an application, please use the link provided below: 
https://apply.deshawresearch.com/careers/Register?pipelineId=865&source=CCL.net

D. E. Shaw Research (DESRES) is a New York-based drug discovery and computational biochemistry 
research company developing and using advanced computational technologies to understand the 
behavior of biologically and pharmaceutically significant molecules at an atomic level of detail, 
and to design precisely targeted, highly selective drugs for the treatment of various diseases.  
Among our core technologies is a proprietary special-purpose supercomputer called ANTON which we 
designed and constructed to perform molecular dynamics simulations more than 100 times faster than 
the world's fastest general-purpose supercomputers.  DESRES develops and refines advanced 
biomolecular modeling methods, software, and machine learning techniques on ANTON, as well as 
on general-purpose supercomputers, in order to pursue both internal and collaborative drug discovery 
programs.

D. E. Shaw Research is an equal opportunity employer, dedicated to the goal of building a diverse 
workforce. We embrace diversity along all dimensions, and respect and value the unique qualities, 
perspectives, and identities of every person in our group. We welcome inquiries from all exceptionally 
well-qualified applicants, regardless of race, color, nationality, national or ethnic origin, religion 
or religious belief, caste, gender identity, pregnancy, caregiver status, age, military service 
eligibility, veteran status, sexual orientation, marital or civil partner status, disability, or 
status in any other category protected in this regard by law in any jurisdiction in which we operate. 

The expected annual base salary for this position is $300,000 - $450,000.  Our compensation package 
also includes variable compensation in the form of sign-on and year-end bonuses, and generous benefits.  
The applicable annual base salary paid to a successful applicant will be determined based on multiple 
factors including the nature and extent of prior experience and educational background.

https://apply.deshawresearch.com/careers/Register?pipelineId=865&source=CCL.net