Position:
Post-doctoral fellows for the Molecular Modeling and Computer-Aided Drug Design 
(CADD) field

Location:
Prof. Sun Choi, Ph.D. 
Director, Global AI Drug Discovery Center
  College of Pharmacy & Graduate School of Pharmaceutical Sciences, 
Ewha Womans University 
52, Ewhayeodae-gil, Seodaemun-gu, Seoul 03760, Korea
  Tel: +82-2-3277-4503 
  Fax: +82-2-3277-2851 
  E-mail: sunchoi(_)ewha.ac.kr 
  Homepage: http://caddsc.ewha.ac.kr/ 

Description:
Ewha Womans University (http://www.ewha.ac.kr/mbs/ewhaen/index.jsp) 
is one of the most prestigious universities in South Korea. Ewha has
continued to evolve throughout its more than 130-year history and now, it
became the largest women's university in the world with 25,000 enrolled
students. The College of Pharmacy in Ewha is the oldest and largest school
of pharmacy in Korea with a history of more than seventy years of Pharmacy
education. Moreover, only the top 1% of excellent students in Korea enter
the College of Pharmacy, and our graduates now number over 10,000. 

In the laboratory of molecular modeling and drug design 
(Prof. Sun Choi; http://caddsc.ewha.ac.kr/), 
various technology and methodology of CADD, cheminformatics, computational
medicinal chemistry and biomolecular simulations are studied. Using
computational methods, we develop strategies for drug discovery involving
cancer, virus, cardiovascular disease, osteoporosis, etc. Adapting to the
target systems, various studies are in progress, including docking and
binding mode analysis, active site and pharmacophore analysis,
structure-activity relationships study and activity/property/toxicity
prediction, chemical library and molecular design (target
structure-/ligand-based), HTS data analysis, hit/lead optimization, study of
molecular interactions and mechanisms, and big data and artificial
intelligence (AI)-based drug discovery. Based on the high-quality and
extensive research outcomes, 

we are continuously publishing articles in world-renowned journals, such as
Journal of the American Chemical Society, Cell Metabolism, Angewandte
Chemie, Journal of Medicinal Chemistry, and Theranostics. Our laboratory was
selected as the National Leading Research Laboratory (NLRL) funded by the
Korean government, and has engaged in active research activities, leading
the Global AI Drug Discovery Center.

  * Research Areas
   - Computer-Aided Drug Design (CADD) Methods and Applications, including
     Docking, Pharmacophore Modeling, Homology Modeling, etc.

   - Protein-Ligand Interaction & their Mechanism of Action Studies 

   - Molecular Design, Combinatorial Library Design, Virtual Screening 

   - Drug Discovery Research for Various Diseases in Cell Signaling

   - Biomolecular Simulations: Protein Motion and Allostery

   - Theoretical Studies of Enzymatic & Chemical Reactions

   - Big Data Analysis and Artificial Intelligence (AI)-based Drug Discovery
	

Required Qualifications:
  - Ph.D. in medicinal chemistry, theoretical/computational chemistry,
    structural biology, bioinformatics, biochemistry or related disciplines

  - *Established record of high-quality scientific research and publications
    in high impact journals

  - Experiences in the fields of QM/MM calculations, MD simulations
    (including enhanced sampling techniques), molecular modeling,
    Computer-Aided  Drug Design (CADD), Big data and AI are preferable

  - Ability to work both independently and as a member of a collaborative,
    scientific team

  - Excellent verbal and written communication skills in English

*Selected eligible candidates will also have the opportunity to apply for a
Korean Government grants covering a program period of 3~5 years.
  - Brain Pool (BP, BP+) Program for inviting outstanding scientists from
  


overseas

To apply:
  - Send an email to sunchoi(_)ewha.ac.kr with the following application list.
    1. Cover letter (describing your research interests and interest in our group)
    2. CV, including publication list
    3. Contact information for 3+ references