D. E. Shaw Research is seeking scientists with experience in computational drug discovery or related areas to join our New York-based team.  This is a unique opportunity to develop and work 
with transformative technology in a dynamic, interdisciplinary environment.

Areas of expertise relevant to our molecular dynamicsbased drug discovery efforts include molecular modeling, machine learning, fragmentbased drug design, cheminformatics, and medicinal 
chemistry.  An ability to leverage experimental data to inform computational approaches would be a plus, as would knowledge of structural biology.  Specific knowledge of any of these areas 
is less critical, however, than strong research skills, and a record of impact in drug discovery.

A successful hire will directly contribute to projects within our expanding portfolio of drug discovery programs, which we pursue both independently and in collaboration with leaders in 
academia and industry.

D. E. Shaw Research develops and uses advanced computational technologies to understand the behavior of biologically and pharmaceutically significant molecules at an atomic level of detail, 
and to design precisely targeted, highly selective drugs for the treatment of various diseases.  Among our core technologies is a proprietary special-purpose supercomputer called ANTON 
which we designed and constructed to perform molecular dynamics simulations more than 100 times faster than the world's fastest general-purpose supercomputers.  DESRES develops and refines 
advanced biomolecular modeling methods, software, and machine learning techniques on ANTON, as well as on general-purpose supercomputers, in order to pursue both internal and collaborative 
drug discovery programs. 

We are looking to add innovative contributors who share our commitment to fostering a stimulating, positive, and collaborative work environment.  
To submit an application, please use the link provided below: 
https://deshawresearch.avature.net/careers/Register?pipelineId=570&source=CCL.net

D. E. Shaw Research is an equal opportunity employer, dedicated to the goal of building a diverse workforce. We embrace diversity along all dimensions, and respect and value the unique 
qualities, perspectives, and identities of every person in our group. We welcome inquiries from all exceptionally well-qualified applicants, regardless of race, color, nationality, 
national or ethnic origin, religion or religious belief, caste, gender identity, pregnancy, caregiver status, age, military service eligibility, veteran status, sexual orientation, 
marital or civil partner status, disability, or status in any other category protected in this regard by law in any jurisdiction in which we operate. 

The expected annual base salary for this position is $300,000 - $475,000.  Our compensation package also includes variable compensation in the form of sign-on and year-end bonuses, 
and generous benefits, including relocation and immigration assistance.  The applicable annual base salary paid to a successful applicant will be determined based on multiple factors 
including the nature and extent of prior experience and educational background. We follow a hybrid work schedule, in which employees work from 
the office on Tuesday through Thursday, and have the option of 
working from home on Monday and Friday.