From chemistry-request#* at *#www.ccl.net Tue Oct 13 12:22:35 1998 Received: from mx02.uni-tuebingen.de (root.,at,.mx02.uni-tuebingen.de [134.2.3.12]) by www.ccl.net (8.8.3/8.8.6/OSC/CCL 1.0) with ESMTP id MAA09515 Tue, 13 Oct 1998 12:22:24 -0400 (EDT) Received: from apollo.pharm.chemie.uni-tuebingen.de (apollo.pharm.chemie.uni-tuebingen.de [134.2.68.23]) by mx02.uni-tuebingen.de (8.8.8/8.8.8) with SMTP id SAA23172 for ; Tue, 13 Oct 1998 18:22:15 +0200 Date: Tue, 13 Oct 1998 18:22:15 +0200 Message-Id: <199810131622.SAA23172: at :mx02.uni-tuebingen.de> X-Sender: cpcmu01 \\at// cpcmu01.mail.uni-tuebingen.de X-Mailer: Windows Eudora Light Version 1.5.2 Mime-Version: 1.0 Content-Type: text/plain; charset="us-ascii" To: chemistry-: at :-www.ccl.net From: Inge Muszynski Subject: bioisosterism Dear CCl'lers, does anybody has an idea how the bioisosteric groups Ester and 1,2,4-Oxadiazole could be aligned in biological targets. I am looking forward to any references or crystallographic data. Inge Muszynski University of Tuebingen Auf der Morgenstelle 8 72076 Tuebingen