Poly-Ala

[Shaun Black <BLACK - at - OHSTPHRM.PHARMACY.OHIO-STATE.EDU>]

It is my recollection that poly-Ala is only sparingly soluble in water,
 but enough can be gotten into solution to do a CD spectrum and see that it
 is alpha helical.  Poly-Gly will probably be more soluble in water, but
 only because it likely unfolds and hydrogen bonds with the solvent.  My
 bet is for "random coil" in water.  It's not clear to me what the
 entropic
 considerations would be, net.  More discussion on this would be interesting.
 =-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=
 Shaun D. Black          | Bitnet: black - at - ohstphrm.bitnet
 Ohio State University   | Internet: black - at -
 ohstphrm.pharmacy.ohio-state.edu
 College of Pharmacy     | Phone: (614) 292-3925
 500 West 12th Avenue    | FAX:   (614) 292-2435
 Columbus, OH 43210-1291 | :-)
 =-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=