The 1998 Charleston Conference
There are a limited number of spaces remaining for the 1998 Charleston
Conference. If you are interested in attending, please send E-mail to
editors { *at * } netsci.org.
The 1998 Charleston Conference
Innovative Techniques for New Lead Discovery and Development
March 9-11, 1998
Wild Dunes Resort
Isle of Palms, South Carolina
Following the highly acclaimed 1997 Charleston Conference, Network
Science Corporation is pleased to announce the distinguished speaker
list for the 1998 conference. This unique annual meeting combines
presentations by industry leaders and an informal atmosphere that affords
the opportunity to interact with colleagues from all phases of research.
Participants will explore the ways in which the industry is increasing the
productivity of the discovery process. We hope you will join us at Wild
Dunes.
Sunday, March 8
8:00 PM: Conference Reception
Monday, March 9
8:00 - 12:00: De Novo and Combinatorial Library Design
Session Chair: Christine Humblet
Senior Director, Biomolecular Structure and Drug
Design, Parke-Davis Research, Warner Lambert
Charles J. Eyermann
Principal Scientist, ARIAD Pharmaceuticals
Presentation: Computational Tools for Maximizing the
Diversity and Druglike Character of Focused Libraries
Irwin ("Tack") D. Kuntz
University of California, San Francisco
Presentation: Combinatorial Chemistry Calculations
William Ripka
Senior Vice President, Chemical Research,
Corvas International, Inc.
Presentation: A Novel Approach to Ligand Design
Utilizing Distance Geometry and the 'Privileged
Structure' Concept
Michael L. Connolly
Computer Consultant
Presentation: Classifying Substrate-Binding Regions
on Proteins by Shape
1:00 - 4:00: High Throughput Screening in ADME/Toxicology
Session Chair: Kate Johnston
Head, Biomolecular Research,
Sphinx Pharmaceuticals, Eli Lilly
Oliver Flint
Principal Scientist, Bristol-Myers Squibb
Presentation: High Throughput Toxicity Testing of
Pharmaceuticals
Jerome Hochman
Research Fellow, Merck Research Laboratories
Presentation: Application of Cell Culture Models to the
Evaluation of Drug Absorption and Drug Metabolism
Ping Yang Yeh
Investigator, Drug Delivery, SmithKline Beecham
Presentation: Combinatorial Screening Approaches for
Selection of Development Candidates
6:30 - 7:30: Poster Session
7:30 PM: Dinner - Sponsored by Molecular Solutions, Inc.
Tuesday, March 10
8:00 - 12:00: Natural Products as a Source for New Leads
Session Chair: John Devlin
President, MicroBotanica, Inc.
John Beutler
Special Expert, Laboratory of Drug Discovery
Research and Development, NCI
Presentation: Informatics, Early Dereplication, and
Natural Products
Donald Bierer
Group Leader, Medicinal Chemistry,
Shaman Pharmaceuticals, Inc.
Presentation: Integrating Modern Science and
Traditional Healing in the Drug Discovery Process
John P. Devlin
President, MicroBotanica, Inc
Presentation: Biochemical Prospecting in the Peruvian
Amazon: A Model of International Collaboration
Wilhelm Stahl
Hoechst Marion Roussel
Presentation: Aspects of Automation in Natural
Products Screening
1:00 - 4:00: Informatics
Session Chair: Jonathan Greene
Director, Technology Development, CombiChem, Inc.
Carleton R. Sage
Principal Scientist, Computational Sciences,
MetaXen LLC
Presentation: Beyond Potency and Selectivity:
Prediction and Optimization of ADME Parameters
Yvonne Martin
Senior Project Leader, CAMD Project,
Abbott Laboratories
Presentation: Better and Better Strategies for Diversity
Selection ... An Update on Abbott Work
Webb Andrews
Research Investigator,
Glaxo Wellcome Research Institute
Presentation: Use of Constrained Properties as a
Basis for the Construction of Combinatorial Libraries
7:00 PM: Tapas Party - Sponsored by Network Science Corporation
Wednesday, March 11
8:30 - 11:30: Gene-Based Drug Design
Session Chair: Susan Burgess
Vice President, Structural Bioinformatics, Inc.
Leigh Anderson
President and CSO, Large Scale Biology Corporation
Presentation: Pharmaceutical Proteomics:
Characterization of Disease Processes and Drug
Mechanisms Through Gene Expression Effects
Donald N. Halbert
Director, Genomics and Molecular Biology,
Abbott Laboratories
Presentation: Genomics-Based Target Discovery:
Expectations and Reality
Rick Fine
Chief Scientific Officer, Paradygm Technologies
Presentation: Protein Surface-Feature Databases: An
Approach to Understanding, Quantitating, and
Comparing Proteins Within and Across Families
Accommodations
The Wild Dunes conference center, located near historic Charleston South
Carolina, offers a variety of activities including 2 1/2 miles of private
beach,
two world class golf courses, several tennis courts, and a heated pool. For
additional information about Wild Dunes, please visit their Website
(http://www.wilddunes.com). Housing will be available
beginning Saturday,
March 7. To facilitate a lively exchange of ideas with colleagues in a casual
setting, attendance at this meeting will be limited.
Other Information
Payments: The conference registration fee is $895 ($695, academic)
which includes all breakfasts, lunches, refreshments, Sunday reception,
Monday evening's dinner, and Tuesday's tapas party. Payments should
be in the form of personal or company check made payable to Network
Science Corporation (EIN: 57-1038302).
About Network Science
Network Science Corporation, a registered non-profit (501(c)3)
organization, was founded in 1995 to assist in science education
and career development within the pharmaceutical and biotechnology
industries. Over the past two years, Network Science, in conjunction
with a number of scientists from the chemical industry, has created
a World-Wide Web site (http://www.netsci.org) which contains
resources dedicated to educational and professional development.
By carefully monitoring trends within the pharmaceutical industry,
Network Science is positioned to organize and present targeted
meetings which address topics of current interest to professionals
within the industry. In addition, the company researches and publishes
industry-wide surveys on topics such as spending and staffing trends,
resource allocation, and technology development.
Call For Poster Session Abstracts
Attendees who wish to present a paper in the Poster Session should
submit an abstract for approval by the Conference Organizing
Committee. The presenter for the poster must be listed as its first
author in the abstract, and each attendee is limited to one presentation
in the Poster Session. Abstracts should be limited to one page,
twelve point font and must contain:
* The title of the presentation
* The names, affiliations, and full contact information for
each of the authors
* The abstract. If structures are part of the abstract, please
submit them separately as a ChemDraw or ISIS Draw
formatted file.
Please note: Only 10 posters will be accepted for presentation at this
conference. If you would like to receive additional details about the
meeting, please contact us at the address below.
The 1998 Charleston Conference
Registration Form
Meeting and Housing
Please Note: This form will reserve your space at the Charleston
Conference. In order to guarantee your reservation, send your payment
and registration form to Network Science at:
Network Science Corporation
412 Carolina Blvd.
Isle of Palms, SC 29451
Tel: (803)886-8775; Fax: (803)886-5924; E-mail: editors { *at * } netsci.org
Name:
Title:
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Phone: Fax: Home Phone:
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Arrival Date (check in 4:00 p.m.)
Departure Date (check out 11:00 a.m.)
Do you need shuttle service from the airport to
Wild Dunes (Fee: $35.00):
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Dietary Restrictions:
Registration fee: Commercial ($895) Academic ($695)
Please note: All accommodations require a three night minimum
stay. A deposit equal to one night's stay ($89/$109) is due with
registration to secure your room reservation. All reservations should
be made as early as possible in order to guarantee specific
accommodations and group rates. Your advance deposit will be
applied to your account or will be returned with 14 days notice
should cancellation be necessary. Should you cancel less than
30 days before arrival, or fail to cancel a reservation, your one
night's deposit will be forfeited. Please note that Wild Dunes is
comprised of privately owned villas; therefore, bedding arrangements
are not standardized as in hotels. Boardwalk suites are comprised
of three or four bedrooms. If you wish to share a suite with colleagues,
please include their names and affiliations.