Summary: SASA programs



Hi all!

 

Thanks to all, for yours comments.

My question  was:

 

Somebody know a free program (with sources, if is possible) to calculate the Surface Area Solvent Accessibility (SASA)?

 

In summary the program available for that are:

MSMS  http://www.scripps.edu/sanner

GPOL93

VEGA  http://users.unimi.it/~ddl

NACCESS    http://wolf.bms.umist.ac.uk/naccess/

MolMol

Sybyl

 

all the answers are follow, and thanks again:

 

cheers!

 

 

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Hi, I think sybyl will do what you want. huajun

 

 

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try http://www.scripps.edu/sanner to find the MSMS program. As I remember, it includes the source.

 

GOOD Lucky!!!

 

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Look for the GEPOL93 code. It is freeware and able to do the things you want,

and more. I found it somewhere on the web.

 

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Our program VEGA (http://users.unimi.it/~ddl) is able to calculate and display SASA and also other molecular surfaces. It reads a lot of file formats and it runs under several operating systems.

 

 --
Dr. Giulio Vistoli
Ist. di Chimica Farmaceutica e Tossicologica
Viale Abruzzi, 42
I-20131 Milano (Italy)
Tel.
+39-02-58357522
Fax +39-02-58357565
E-Mail:
giulio.vistoli #*at*# unimi.it
WWW:
http://users.unimi.it/~ddl

 

 

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There is the program MSMS of Michel Sanner that compute solvent excluded surface (SES) and that should also compute Solvent Accessible (SAS). Try also the Vega package.

I do not have the link right now but you should find it easily with a good search engine.

 

Cheers,

--

Fabien Fontaine

Engineer in Biotechnology

Research Group on Biomedical Informatics, IMIM/UPF

Doctor Aiguader, 80

E-08003 Barcelona (SPAIN)

Tel: (34) 93 221 1009 Ext: 2340

Fax: (34) 93 221 3237

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   NACCESS

    http://wolf.bms.umist.ac.uk/naccess/

 

cheers,

 

Malcolm

--

Malcolm Gillies <malcolm.gillies #*at*# kemi.dtu.dk>

Post-doctoral researcher

Organic Chemistry, Dept Chemistry,

Technical University of Denmark

 

 

 

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Dear Mr. Gonzalez,

 

there are several programs to calculate the surface of molecules. A good point to start is Michael Sanners MSMS.The Swiss-PDB Viewer can calculate the surface of proteins. gOpenMol can calculate the Connolly surface. Molekel has a version of MS, which also can calculate Connolly surfaces.

 

Hope this helps,

 

-------------------------------------------------

Christoph Nimptsch

Apotheker

Pharmazeutisches Institut

Arbeitskreis Prof. Kovar

Universität Tübingen

Auf der Morgenstelle 8

D-72076 Tuebingen

Tel.: 07071/2978794

mailto:christoph.nimptsch #*at*# uni-tuebingen.de

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MolMol will do it. It has nice graphical interface and source is provided.

 

Hope this helps,

 

Mire Zloh

School of Pharmacy

29 Brunswick Square

London WC1N 1AX

 

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try Michel F. SANNER's MSMS:

 

Sanner, M.F., Spehner, J.-C., and Olson, A.J. (1996) Reduced surface: an efficient way to compute molecular surfaces. Biopolymers, Vol. 38., (3), 305-320.

 

you can get #*at*# http://www.scripps.edu/sanner.

 

hope it helps & best regards

 

felipe

 

 

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I recently used SIMS, by Yury N. Vorobjev  (Biophysical Journal,73:722-732; 1997); You can get the free source software at:

 

http://femto.med.unc.edu/SIMS/

 

François Sampieri

 

 

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Actually, it is in the CCL archives:

 

http://www.ccl.net/cca/software/SOURCES/FORTRAN/molecular_surface/gepol93/index.shtml

 

--

Marcel Swart

 

Theoretische Chemie (MSC) / Moleculaire Dynamica (GBB)

Rijksuniversiteit Groningen

Nijenborgh 4

9747 AG Groningen

The Netherlands

m.swart #*at*# chem.rug.nl

http://go.to/m.swart

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that’s all..

 

...........................................................................................

Danilo Gonzalez-Nilo

University of Santiago of Chile

Faculty of Chemistry and Biology

Casilla 40, Correo 33,

Santiago - Chile.