Re: CCL:Marketed drugs by structure-based design?



 Hi Renxiao,
 One review I can think of the top of my head is
 
Donald B. Boyd, Successes of Computer-Assisted Molecular Design, pp. 355-371., 1990 It is a little outdated, but nevertheless mentions four drugs that made it to the market.
 Hope this helps,
 Carsten
 Renxiao Wang wrote:
 
 Hi, all!
 Would anybody please provide some references for marketed drugs whose
 development were largely aided by structure-based design methods? Some
 review papers/books must have mentioned this, but I cannot recall any at
 this moment.
 Any clue is appreicated. I will put back the summary. Thanks in
 advance!
 Regards,
 --------------------------------------------------------------------------------------------------
 Renxiao Wang, Ph.D.
 Research Investigator
 Department of Internal Medicine, Hematology/Oncology Division
 University of Michigan Medical School
 Ann Arbor, MI 48109, U.S.A.
 Tel: (734) 764-2449; Fax: (734) 764-2532
 E-mail: renxiao!at!med.umich.edu
 Web: http://sw8.im.med.umich.edu/~arthur/
 --------------------------------------------------------------------------------------------------
 -= This is automatically added to each message by the mailing script =-
 To send e-mail to subscribers of CCL put the string CCL: on your Subject: line
 and send your message to:  CHEMISTRY!at!ccl.net
 
Send your subscription/unsubscription requests to: CHEMISTRY-REQUEST!at!ccl.net HOME Page: http://www.ccl.net | Jobs Page: http://www.ccl.net/jobs
 If your mail is bouncing from CCL.NET domain send it to the maintainer:
 Jan Labanowski,  jlabanow!at!nd.edu (read about it on CCL Home Page)
 -+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+
 
 --
 Carsten Detering, Ph.D.
 University of Washington
 Department of Chemistry
 Box 351700
 Seattle, WA 98195-1700
 Fon 206.543.5081
 Fax 206.685.8665