Bio.com Life Sciences News Update
July 24, 2002
Produced by Bio Online(r)
Portal to the Life Sciences(tm)
www.bio.com | www.bioprotocol.com
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CONTENTS:
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1. Science News: "Gene Therapy Halts Heart Failure in Animals"
2. InFocus: "Pharmacogenomics" - Transcript and mp3 now available
3. Career Center: The "Next Generation" Career Center is here
4. Jobs of the Week: "Scientist" and others
5. Market Research: "The Competitive Landscape of Cancer Gene Therapy"
6. Featured Software: "ACD/ChemSketch" and others
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Newsletter Sponsored by: IBM
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Life sciences data is growing quickly. IBM's portfolio of data management
solutions for the life sciences includes DB2(r) Universal Database. DB2 has
the capabilities you need for research. Example: the ability to handle data
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data needs change our solutions will grow with you. For more information
on DB2 for the life sciences and to order a free data management CD go to
http://www.ibm.com/solutions/lifesciences/r/db2e43
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1. SCIENCE NEWS
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-Critical Clue to Congenital Heart Abnormalities
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=1
Researchers led by a University of Utah physician have discovered a key clue
in what causes one of the most common congenital heart problems-defective
valves. The problem, atrioventricular septal defects (AVSD), occurs when the
polysaccharide hyaluronan (HA), one of the most common substances in the
body, is absent during the early stages of heart formation, the researchers
say in the July 22 edition of Nature Medicine.
-Faulty Gene May Explain High Altitude Sickness
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=2
Two slight variations in a gene that helps maintain lung function increase
the risk of high altitude sickness, a rare but potentially deadly breathing
disorder, according to a report in Circulation: Journal of the American
Heart Association. The findings may also help researchers find causes of
other lung disorders. These include chronic mountain sickness, primary
pulmonary hypertension, emphysema and chronic bronchitis.
-Gene Therapy Halts Heart Failure in Animals
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=3
Researchers at the University of California, San Diego (UCSD) School of
Medicine have developed a therapeutic gene and molecular delivery system
that provides successful long-term gene therapy that halts chronic heart
failure in experimental animals.
-Prostate Cancer Tracking System Developed
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=4
UCLA Researchers have demonstrated for the first time that they can locate
difficult-to-detect prostate cancer metastases in laboratory models, a
discovery that could lead to safer and more effective gene-based treatments
for advanced prostate cancer. They engineered a virus that can identify
prostate cancer cells based on the prostate-specific antigen (PSA) protein
expressed only in prostate cells.
-First Genome-Wide View of RNA Splicing
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=5
A surprising amount of the DNA sequence in the genes of humans and other
higher organisms ends up on the cutting-room floor, so to speak, spliced out
by the cellular machinery that turns genetic code into functional proteins.
Differences in the editing of genetic information may, in fact, be a
significant source of genetic variability. Researchers at the University of
California, Santa Cruz, have now taken a big step toward understanding how
splicing is regulated.
-FEATURE: The Coming Of The Nano-Age
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=6
The emerging fields of nanoscience and nanoengineering are leading to
unprecedented understanding and control over the fundamental building blocks
of all physical things. This is likely to change the way almost
everything-from vaccines to computers to automobile tires to objects not yet
imagined-is designed and made.
-FEATURE: The Building Blocks of Nanotechnology
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=7
Designing, synthesizing and characterizing new types of nano-building blocks
will be a major mission for materials scientists. These building blocks will
come in a variety of shapes and sizes, and will be fashioned from inorganic
or "hard" matter, organic or "soft" matter, and sometimes from a mixture of
both. Time will tell what forms these building blocks may eventually take,
but among the many promising shapes are three basic varieties- crystals,
tubes, and a tree-like, heavily-branched class of polymers called
"dendrimers."
To view Industry news, visit:
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml
To view Research news, visit:
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml
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2. INFOCUS WEBCAST
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1) "Pharmacogenomics: Applications in Drug Development"
Broadcast Wednesday, July 10, 2002
*Click here to view the PDF transcript:
http://www.bio.com/file_temp/pharmacogenomics02.pdf
*Click here to listen to the audio recording:
http://chat.bio.com:8000/audio/pharmacogenomics_071002.mp3
*Click here to enter a drawing for a giveaway from our sponsors:
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=8
*To view all past InFocus Webcast recordings and transcripts, go to:
http://www.bio.com/newsfeatures/newsfeatures_fochives.jhtml
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3. CAREER CENTER
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Tired of searching for jobs day after day?
Let Bio.com do the job search for you!
Bio.com works on behalf of selected employers in the life sciences industry to
look for top candidates like you. It's a personalized service that ensures:
-You will ONLY be contacted for positions that FIT your background.
-Strict Confidentiality: Unlike other sites that allow recruiters full access to
their resume database, Bio.com will maintain your anonymity until you choose to
be contacted by any given employer.
As a Bio.com Member, you will also enjoy Bio.com's new Career Center Tool
that allows you to:
-Gain access to thousands of life sciences job opportunities
(http://www.bio.com/careercenter/seekers/jobs_by_employer.jhtml)
-Receive Job Agent alerts for jobs that match your criteria
-Apply for jobs with a one click application process
-Maintain/store your resume confidentially
-Receive monthly e-newsletter with "Featured Jobs" and "Featured Employers"
These services are FREE for you to use. So, what are you waiting for?
Sign up for your Bio.com Membership and start your job search today!
http://www.bio.com/careercenter/index.jhtml
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4. JOBS OF THE WEEK
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Look at what's new in the Bio.com Career Center this week:
1. Guava Technologies: Scientist, R&D Applications
http://www.bio.com/careercenter/seekers/view_job.jhtml?id=8300015
2. CV Therapeutics: Associate/Senior Associate, Quality Assurance
http://www.bio.com/careercenter/seekers/view_job.jhtml?id=7000007
3. Setren Smallberg & Associates: Process Engineer
http://www.bio.com/careercenter/seekers/view_job.jhtml?id=7400007
4. Eli Lilly & Company: Microbiology Lead
http://www.bio.com/careercenter/seekers/view_job.jhtml?id=777935
5. CTL ImmunoTherapies: Scientist
http://www.bio.com/careercenter/seekers/view_job.jhtml?id=8600002
Register today and start using our new features:
http://www.bio.com/careercenter/seekers/index.jhtml
Click here to browse all jobs from Bio.com's Career Center:
http://www.bio.com/careercenter/seekers/jobs_by_employer.jhtml
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5. MARKET RESEARCH
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Bio.com offers the most comprehensive collection of market research.
-The Emerging Bio-IT Market: The Convergence of IT and Biopharmaceutical
R&D - In-Silico High Performance Systems, Services, Opportunities and Market
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=9
The combination of the bioscience industry with the information technology
(IT) industry is emerging as an exciting industry segment that is being
called bio-IT. The bio-IT market is emerging at an important time when the
bioscience companies need enormous computing power to make sense of the
flood of data that is being generated in drug discovery R&D labs.
Ironically, this is also an important time for the IT industry, which is
hungry for new customers in the slow economy. This report seeks to review
all the key elements of this interesting and important market.
-The Competitive Landscape of Cancer Gene Therapy
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=10
Cancer is not one single disease but can be divided into almost 200
different diseases. In the United States, overall annual costs associated
with cancer currently amount to $107 billion and the worldwide anti-cancer
market, valued at more than $15 billion in 1998, is projected to nearly
double by 2003. Based on advances in cell and molecular biology, the number
of therapeutic cancer targets in the pipeline is rapidly increasing.
Numerous long-standing pharma companies as well as young biotechnology
firms are driving cancer research today and in the future. This report
provides a complete and thorough description of the current cancer gene
therapy pipelines.
-C.H.I. Patent Profiles
http://www.bio.com/Redirectors/LinkRedirect7_15.jhtml?link=10
CHI Research, Inc. is a worldwide leader in Intellectual Property
consulting. Their analysts are recognized leaders in their field, and their
databases of patents are unparalleled in their accuracy. No other
Intellectual Property consulting firm can match the level of detail in CHI's
technology evaluations. These patent profiles offer concise, actionable
intelligence on the technological strengths and weaknesses of companies,
government agencies, academic institutions, and nonprofit organizations.
One of the fundamental drivers of a company's future success is the quality
of its technology. C.H.I. Patent Profiles provide unique quantitative
measures of that quality, allowing one company to be compared with
competitors over time and technology-by-technology..
Click here to browse through our publications catalogue:
http://www.bio.com/store/store_publications.jhtml
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6. FEATURED SOFTWARE
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Bio.com offers a very comprehensive selection of Life Science related
software. Check out these latest additions:
-Beacon Designer 2
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=11
Molecular beacon, TaqMan(r) probe and primer pair design software for
Windows.
Design real time pcr probes and primer pairs with a click of a button.
Designs beacons free of dimers, repeats, and runs for increased signal
strength. Avoids cross homologies with all primers preventing competition
in multiplex reactions. Designs molecular beacons for detection of both
wild and mutant alleles.
-Genamics Expression
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=12
Expression is a revolutionary new application for DNA and protein sequence
analysis. Utilizing a novel interface, Expression makes complex
computational analyses of sequence information incredibly simple. Expression
uses the very latest computing technology to set new standards in the way
sequences are analysed.
-ACD/ChemSketch
http://www.bio.com/Redirectors/LinkRedirect7_23.jhtml?link=13
Quickly and easily draw molecules in a chemistry-oriented interface.
Instantly calculate the chemical formula, molecular weight, percentage
composition. Predict several liquid properties such as density and
refractive index. Customize display properties, e.g., atom numbering,
chemical symbols, and valence. Draw reactions, schematic diagrams and
design other chemistry-related reports and presentations. Work with
structures, text and graphics simultaneously and transfer to any
OLE-supported software.
Click here to browse through our software catalogue:
http://www.bio.com/store/store_software.jhtml
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Copyright (c) 2002 Bio Online, Inc. All rights reserved.
Received on 2002-07-24 - 06:07 GMT
This archive was generated by hypermail 2.2.0 : 2005-11-24 - 10:21 GMT