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Date: Thu, 06 Apr 1995 13:55:59 +0100
To: chemistry |-at-| ccl.net
From: kamal /at\univ-orleans.fr (Kamal Azzaoui)
Subject: Log P (o/w) of octanol !


Dear netters

We are working in the field of quantitative structure-chromatographic
retention relationships (QSSR) and ,
among various physico-chemical descriptors, we used the calculated Log P
(o/w)( With Ghose and Crippen=92s parameters).

One of our products is Octanol.

It is very easy to calculate the Log P of Octanol ( we found 2.54), this
value is a by evidence a descriptor of the structure , but we have a
=91philosophic=92 problem:

What is the physical meaning of Log P(o/w) of Octanol?
Subsidiary question: What is the Log P of water?

All suggestions are welcome !!=20

thanks

Kamal=20
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        Kamal AZZAOUI                                   =20

   LCBA. Universit=E9 d'Orl=E9ans.
     BP 6759.
   45067 Orl=E9ans cedex 2
        France
   Tel: 38-41-70-42
   email: kamal.,at,.centre.univ-orleans.fr
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