Postdoctoral position available
- From: "Richard C. Elder, Chemistry, U of Cincinnati"
<Dick.Elder at.at
UC.EDU>
- Subject: Postdoctoral position available
- Date: Mon, 1 Apr 1991 16:30 EST
Dear Colleague:
The following is an announcement of a postdoctoral position
currently open in my lab. I would appreciate your bring this
to the notice of any individuals who might be interested.
Thanks. Dick Elder
**********************************************************************
Postdoctoral Position
Structural Determination of Amorphous Metal Complexes
Using Molecular Modeling and Synchrotron X-Ray Investigations
A position is currently available in the Elder group at the
University of Cincinnati. The project centers on the elucidation
of the structures of rhenium diphosphonate materials used as
palliatives for metastatic prostate and breast cancer which has
spread to bone. We use techniques such as EXAFS spectroscopy and
Wide angle X-ray scattering / differential anomalous scattering
(WAXS/DAS) to develop one-dimensional radial distribution
functions describing the environment of the metal atom of
interest. We are now trying to extend this information to three-
dimensional models using the techniques of molecular modeling as
extended to metal complexes. Experiments are conducted at NSLS
(Brookhaven) and SSRL (Stanford). Calculations are performed at
the University of Cincinnati on a Silicon Graphics TG35 and via
ethernet link on the Ohio Supercomputer Center Cray Y-MP. A
general reference to our work with metal-based drugs is R.C.
Elder and M.K. Eidsness, Chem. Rev., 1987, 87, 1027; a specific
reference to our work with diphosphonates is J.L. Martin et al.,
Inorg. Chem., 1989, 28, 2899. Interested individuals should
respond to Professor Richard C. Elder, Acting Director,
Biomedical Chemistry Research Center, Department of Chemistry,
University of Cincinnati, Cincinnati Ohio, 45221-0172. Send a CV
and date of availability, also ask two references to write
concerning your qualifications. More rapid communication is
available via Internet to Dick.Elder at.at UC.EDU. Faxed materials may
be sent to (513) 556-9239. Telephone, (513) 556-9224, for
further details.