From rswenson@magnus.acs.ohio-state.edu Mon Aug 1 22:13:19 1994 Received: from beauty.magnus.acs.ohio-state.edu for rswenson@magnus.acs.ohio-state.edu by infomeister (8.6.9/930601.1506) id VAA21969; Mon, 1 Aug 1994 21:44:22 GMT From: Received: from swens1.biosci.ohio-state.edu by beauty.magnus.acs.ohio-state.edu (8.6.4/4.940426) id RAA20664; Mon, 1 Aug 1994 17:49:54 -0400 Message-Id: <199408012149.RAA20664@beauty.magnus.acs.ohio-state.edu> X-Sender: rswenson@magnus.acs.ohio-state.edu Mime-Version: 1.0 Content-Type: text/plain; charset="us-ascii" Date: Mon, 01 Aug 1994 17:45:06 -0400 To: chemistry@ccl.net Subject: Macromolecular modeling review X-Mailer: I am involved in the organization of a special topics course for graduate students (principally in Biochemistry and the biological sciences) covering various aspects of "protein engineering". We would like to include a component this year covering the use of computational methods for the modelling of mutated protein structures, particularly with respect to predicting the structural consequences of amino acid substitutions. Another aspect that could be included is the application of such methods in the _de novo_ design of novel protein structures. I would greatly appreciate input from the group as to any good, general review articles, books, etc. that would introduce the basics to students with general biochemical training and varied expertise in the subject area. Thank you. *********************************************************************** * Richard P. Swenson | ..... ..... . . * * Dept of Biochemistry | Tel: 614-292-9428 . . . . . * * Ohio State University | FAX: 614-292-6773 . . ..... . . * * 484 West 12th Avenue | Swenson.1@osu.edu . . . . . * * Columbus, OH 43210 | ..... .... ..... * ***********************************************************************