From kamal@univ-orleans.fr Thu Apr 6 09:14:51 1995 Received: from centre.univ-orleans.fr for kamal@univ-orleans.fr by www.ccl.net (8.6.10/930601.1506) id JAA27342; Thu, 6 Apr 1995 09:07:04 -0400 Received: from mailhost.univ-orleans.fr ([193.49.81.2]) by centre.univ-orleans.fr (8.6.9/8.6.9) with SMTP id PAA27616 for ; Thu, 6 Apr 1995 15:12:25 +0200 LD?Resent-Date: Thu, 6 Apr 1995 15:12:25 +0200 Message-Id: <199504061312.PAA27616@centre.univ-orleans.fr> X-Sender: kamal@mailhost.univ-orleans.fr X-Mailer: Windows Eudora Version 1.4.4 Mime-Version: 1.0 Content-Type: text/plain; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable Date: Thu, 06 Apr 1995 13:55:59 +0100 To: chemistry@ccl.net From: kamal@univ-orleans.fr (Kamal Azzaoui) Subject: Log P (o/w) of octanol ! Dear netters We are working in the field of quantitative structure-chromatographic retention relationships (QSSR) and , among various physico-chemical descriptors, we used the calculated Log P (o/w)( With Ghose and Crippen=92s parameters). One of our products is Octanol. It is very easy to calculate the Log P of Octanol ( we found 2.54), this value is a by evidence a descriptor of the structure , but we have a =91philosophic=92 problem: What is the physical meaning of Log P(o/w) of Octanol? Subsidiary question: What is the Log P of water? All suggestions are welcome !!=20 thanks Kamal=20 ------------------------------------------------------------------ Kamal AZZAOUI =20 LCBA. Universit=E9 d'Orl=E9ans. BP 6759. 45067 Orl=E9ans cedex 2 France Tel: 38-41-70-42 email: kamal@centre.univ-orleans.fr ------------------------------------------------------------------