Log P (o/w) of octanol !
Dear netters
We are working in the field of quantitative structure-chromatographic
retention relationships (QSSR) and ,
among various physico-chemical descriptors, we used the calculated Log P
(o/w)( With Ghose and Crippen?s parameters).
One of our products is Octanol.
It is very easy to calculate the Log P of Octanol ( we found 2.54), this
value is a by evidence a descriptor of the structure , but we have a
?philosophic? problem:
What is the physical meaning of Log P(o/w) of Octanol?
Subsidiary question: What is the Log P of water?
All suggestions are welcome !!
thanks
Kamal
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Kamal AZZAOUI
LCBA. Université d'Orléans.
BP 6759.
45067 Orléans cedex 2
France
Tel: 38-41-70-42
email: kamal -AatT- centre.univ-orleans.fr
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