Re: Searching for sequences
Jeff,
If you have access to Sybyl from Tripos, the "Search Protein
Database" item
on the Biopolymer menu supports the kind of query you specified
(Asn-X-Glu), and provides convenient access to view and analyze the
resulting 3D fragments and perform more complex searches. BTW, I did a
quick search of that pattern on a non-redundant subset of 343 structures
from the PDB, and got 227 hits. A quick followup search revealed that 38
of these 3-residue fragments are fully contained within alpha helices, and
14 are fully contained within beta strands.
Let me know if you'd like more information.
David Mosenkis (david' at \`tripos.com)
Tripos, Inc.