From didier@pharma.ethz.ch Tue Jan 23 07:45:32 1996 Received: from pharma6.ethz.ch for didier@pharma.ethz.ch by www.ccl.net (8.6.10/950822.1) id HAA10004; Tue, 23 Jan 1996 07:32:34 -0500 Received: from pharma53 ([130.60.204.236]) by pharma6.ethz.ch with SMTP id AA12859 (5.65c/IDA-1.4.4 for ); Tue, 23 Jan 1996 13:13:59 GMT Date: Tue, 23 Jan 1996 13:13:59 GMT Message-Id: <199601231313.AA12859@pharma6.ethz.ch> X-Sender: didier@pharma6.ethz.ch X-Mailer: Windows Eudora Light Version 1.5.2 Mime-Version: 1.0 Content-Type: text/plain; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable To: chemistry@www.ccl.net, chem-mod%mailbase@ac.uk, dibug@comp.bioz.unibas.ch, hyperchem@hyper.com, isisforum-l@mdli.com, mmodinfo@uoft02.utoledo.edu, pmd@cumbnd.bioc.columbia.edu, quanta-l@msi.com, sybyl@extreme.chem.rpi.edu, anchodd@cc.utas.edu.au, mmodlist@chem.iupui.edu From: Didier Rognan Subject: Second Swiss Course on Medicinal Chemistry Second Swiss Course on Medicinal Chemistry 6-11 October 1996, Leysin, Switzerland organized by the Section of Medicinal Chemistry of the New Swiss Chemical Society SCOPE OF THE COURSE The course on medicinal chemistry offers to young scientists with a few years of experience in the pharmaceutical industry and interested Ph.D. students a broad overview of disciplines involved in modern preclinical drug research. The development of integrative abilities is a prerequisite to function in todays multidisciplinary drug discovery teams. The course is set up for synthetic organic chemists, as well as biologists and pharmacologists and those involved in drug design and the physicochemical characterization of biologically active compounds. Active participation by the participants in tutorials and the presentation of three case histories are important parts of the course. PROGRAMME AND LECTURERS=09 What is medicinal chemistry? Prof. B. Testa (Uni. Lausanne, CH) =09 Molecular & Cell Biology=09 What are the targets for the medicinal chemist Dr. W. Schilling (Ciba, Basle - CH) Introduction to molecular biology Prof. T.H. Schwartz (Uni. Copenhagen, DK) Integration of molecular biology with medicinal chemistry Prof. T.H. Schwartz (Uni. Copenhagen, DK) Introduction to molecular immunology Dr. J.-Y. Bonnefoy (Glaxo, Geneva - CH) =09 Lead Finding & Development=09 Lead discovery Dr. M. Sills (Ciba, Summit - USA) Introduction to combinatorial chemistry Dr. E. Feder (Ciba, Basle- CH) Developing a lead Dr. D. Roberts (Zeneca, Macclesfield - UK) Patents and regulatory apects Dr. R. Ross (Sandoz, Basle - CH) =09 Pharmacodynamics=09 Principles of pharmacological assays Prof. H. M=F6hler (Uni. Z=FCrich, CH) Ion channels as drug targets Prof. U. Quast (Uni. T=FCbingen, D) =09 Phamacokinetics, Toxicology & Drug Delivery=09 Introduction to pharmacokinetics Prof. H. Spahn-Langguth (Uni. Halle, D) Introduction to drug metabolism Prof. B. Testa (Uni. Lausanne, CH) Introduction to molecular toxicoloy Prof. N.P.E. Vermeulen (Uni. Leiden, NL)= =20 Formulation and drug delivery Prof. D. Crommelin (Uni. Utrecht, NL) =09 Molecular Design & Lead Optimization=09 Physicochemical concepts and drug absorption Dr. H. van de Waterbeemd (Roche, Basle - CH) Molecular modeling Prof. G. Folkers (ETH Z=FCrich, CH) Computer-assisted lead optimization Prof. H. Kubinyi (BASF, Ludwigshafen -= D) =09 Case Histories=09 Development of aromatase inhibitors Prof. A. Bhatnagar (Ciba, Basle - CH) The story of LESCOL Dr. F. Kathawala (Sandoz, East Hanover - USA) Development of INVIRASE Dr. J. Lawton (Roche, Welwyn - UK) =09 ORGANIZATION Prof. Gerd Folkers (ETHZ, chairman), Dr. H. van de Waterbeemd (Roche, vice-chairman)=20 Dr. W. Froestl (Ciba), Dr. R. Jakob-Roetne (Roche), Dr. D. Rognan (ETHZ), Prof. B. Testa (Uni. Lausanne), Dr. R. Wenger (Sandoz) WORLD WIDE WEB A description of the course including programme, location, accomodation facilities and registration form can be found at the following URL: http://www.pharma.ethz.ch/leysin PRACTICAL INFORMATIONS Location The course will be held at the Classic Hotel in Leysin, Switzerland. In the heart of the =93Alpes Vaudoises=93 and within easy reach of the towns of the Lake Geneva Region, Leysin is the perfect answer to the wishes and expectations of all those who love nature, winter and summer sports, walks, good food, the opportunity to meet interesting people, relaxation. =09 =09 Hotel The Classic is the largest hotel in Leysin, within the spirit of the resort. It offers a large array of single and double rooms, bars, restaurants, terrace, auditorium/cinema, gastronomic events. Registration fees=09 The individual fee of Sfr 2500,- includes hotel accomodation with breakfast, course documentation, coffee breaks, lunches and dinner. Students pay a special price of only SFr 250,- (please include justification to your registration) Registration The registration form should be returned before the end of April 1996. The course is limited to about 60 participants. Confirmation and payment instructions will be sent to all accepted participants. Late registrations after May 1st 1996 will require 10% additional fee.=09 =09 Arrival=09 Sunday October 11, 1996 in the afternoon. Welcome drink at 6 p.m. Language The official language of the course is English.=09 =09 ". . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .=20 REGISTRATION FORM Second Swiss Course on Medicinal Chemistry (6-11 October 1996, Leysin, Switzerland) Name . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . =20 Organization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Address . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .=20 Zip Code . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . City . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Country . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Present function . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .=20 Tel: . . . . . . . . . . . . . . . . . . . . . Fax: . . . . . . . . . . . . . . . . . . . . . E-mail: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Signature . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Date . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Please return this form to:=20 Prof. Gerd Folkers, Dpt. of Pharmacy - ETH Wintherturerstrasse 190- CH-8057 Z=FCrich, Switzerland Tel. +41.1.257 60 60, Fax: +41.1.262 15 80, E-mail: folkers@pharma.ethz.ch Payments should be made to: Bankaccount 0061-867802-80-1 of Cr=E9dit Suisse Claraplatz, CH-4005 Basel, Switzerland. (Ref: Swiss Med Chem) ----------------------------------------------------------- Dr. Didier Rognan Department of Pharmacy - ETH Winterthurerstr.190, Room I17M50 CH-8057 Zuerich phone:+41.1.257 60 63 fax: +41.1.262 15 80 email: didier@pharma.ethz.ch www: http://www.pharma.ethz.ch/~didier -----------------------------------------------------------