Help! InsightII Counter Ions

From: John Cox <che5jwc &$at$& titan.vcu.edu>
Organization: VCU
Subject: Help! InsightII Counter Ions
Date: Mon, 21 Jul 1997 13:50:00 -0400

 Hello,
 I am working with oligonucleotides generated in the Biopolymer module by
 Insight and am wondering how to incorporate counter ions to balance the
 charge of the system to 0. The strands separate when optimized with
 Discover seemingly because of phosphate charge repulsions, and I think
 generic counter cations will correct this problem. Suggestions on how to
 generate/incorporate these charges will be greatly appreciated, thanks.
 Cheers,
 John Cox
 Graduate Student
 Dept. of Chemistry
 Virginia Commonwealth University
 Richmond, VA
 804 828-0276
 che5jwc &$at$& titan.vcu.edu