From netsci@awod.com Wed Sep 17 11:24:50 1997 Received: from sumter.awod.com for netsci@awod.com by www.ccl.net (8.8.3/950822.1) id LAA18703; Wed, 17 Sep 1997 11:03:15 -0400 (EDT) Received: from [208.140.96.13] (chs0016.awod.com [208.140.96.16]) by sumter.awod.com (8.8.7/8.8.5) with SMTP id LAA00460; Wed, 17 Sep 1997 11:03:08 -0400 (EDT) X-Sender: arichon@awod.com Message-Id: Mime-Version: 1.0 Content-Type: text/plain; charset="us-ascii" Date: Wed, 17 Sep 1997 11:00:59 +0100 To: chemistry@www.ccl.net From: netsci@awod.com (Network Science) Subject: Meeting Announcement for 1998 Charleston Conference Cc: netsci@awod.com Status: RO Content-Length: 6041 The 1998 Charleston Conference Innovative Techniques for New Lead Discovery and Development March 9-11, 1998 Wild Dunes Resort Isle of Palms, South Carolina At one time, pharmaceutical scientists studied the function and structure of a novel biological target and spent years identifying and optimizing a lead candidate. Over the past few years, competitive pressures have forced research to become more efficient. Emerging new technologies such as genomics, gene sequencing, transgenic animals, and molecular biology have afforded large numbers of novel, clinically relevant biological targets. High throughput screening and combinatorial chemistry have been used to rapidly identify and optimize leads for these targets. Additionally, the complementary techniques of computational chemistry and cheminformatics have been used to successfully leverage research information. The invited lectures and round-table discussions to be held over two and one-half days will focus on the successful integration of these technologies in new lead discovery and development. Participants will explore the ways in which the industry is increasing the productivity of the discovery process. The outstanding group of invited session chairs and speakers who will lead the meeting are listed below. Monday, March 9 8:00 - 11:30 Informatics Session Chair: David Spellmeyer Director, Design Technology Applications CombiChem, Inc. Ajay Jain Principal Scientist, Computational Sciences MetaXen LLC Yvonne Martin Senior Project Leader Computer Assisted Molecular Design Project Abbott Laboratories Webb Andrews Research Investigator Glaxo Wellcome 12:30 - 3:30 High Throughput Screening in ADME/Toxicology Session Chair: Kate Johnston Head, Biomolecular Research Sphinx Pharmaceuticals, Eli Lilly Oliver Flint Principal Scientist Bristol-Myers Squibb Jerome Hochman Research Fellow Merck Research Laboratories Philip L. Smith Director, Drug Discovery SmithKline Beecham 6:00 - 7:00: Poster Session 7:00 - 8:30: Dinner Sponsored by Molecular Solutions, Inc. 8:30 - 10:30: Vendor Q&A Tuesday, March 10 8:00 - 11:30: De Novo and Combinatorial Library Design Session Chair: Christine Humblet Senior Director Biomolecular Structure and Drug Design Parke-Davis Research, Warner Lambert Joe Eyermann Principal Research Scientist Dupont-Merck Pharmaceuticals Irwin ("Tack") D. Kuntz University of California, San Francisco William Ripka Senior Vice President, Chemical Research Corvas International, Inc. 12:30 - 3:30 Natural Products as a Source for New Leads Session Chair: John Devlin President ARRT International John Beutler Special Expert Laboratory of Drug Discovery Research and Development National Cancer Institute Donald E. Bierer Group Leader Medicinal Chemistry Shaman Pharmaceuticals, Inc. John P. Devlin President MicroBotanica, Inc Wilhelm Stahl Director of Screening Hoechst Marion Roussel 7:00 - 10:30: Tapas Party 412 Carolina Boulevard Wednesday, March 11 8:00 - 11:30: Gene-Based Drug Design Session Chair: Susan Burgess Vice President Structural Bioinformatics, Inc. Leigh Anderson President and CSO Large Scale Biology Corporation Donald N. Halbert Director, Genomics and Molecular Biology Abbott Laboratories Mark Furth Chief Scientific Officer PPD Inc. The Accommodations The Wild Dunes conference center offers a variety of activities including two world class golf courses, several tennis courts, and a heated pool. Housing will be available beginning Saturday, March 7. To facilitate a lively exchange of ideas with colleagues in a casual setting, attendance at this meeting will be limited. Call For Poster Session Abstracts Attendees who wish to present a paper in the Poster Session should submit an abstract for approval by the Conference Organizing Committee on or before October 31, 1997. The presenter for the poster must be listed as its first author in the abstract, and each attendee is limited to one presentation in the Poster Session. Abstracts should be limited to one page, twelve point font and must contain: * The title of the presentation * The names, affiliations, and full contact information for each of the authors * The abstract. If structures are part of the abstract, please submit them separately as a ChemDraw or ISIS Draw formatted file. The Charleston Conference Committee will notify authors of acceptance of their poster by November 30. Please Note: Only 10 posters will be accepted for presentation at this conference. If you would like to be contacted with additional details about the meeting, please use this e-mail link and give us your name, e-mail address, and telephone and Fax number. Electronic registration is available at http://www.netsci.org Network Science Corporation 412 Carolina Blvd Isle of Palms, SC 29451 Tel: (803)886-8775 Fax: (803)886-5924 E-mail: netsci@awod.com URL: http://www.netsci.org