GPCRs and other non-structural targets

From: Daniel Severance <dseverance ^at^ acadia-pharm.com>
Subject: GPCRs and other non-structural targets
Date: Wed, 16 Feb 2000 14:13:12 -0800

Hi,
     Does anyone have a summary of what research groups are working on
 computational methods for dealing with things where no structures are known?
 I.e., given the structures of a series of small molecules and their
 activities, trying to infer something about what interactions must be
 important?
     Also, for those of you who may have hired people to work on these kinds
 of problems - what background have you found is best (assuming they did
 something different as a student).  Thanks.
     Feel free to e-mail me directly and I'll summarize to the list.
     Dan
 ____________________________________________________
 Daniel L. Severance Ph.D.                             phone  (858) 558 2871
 Computational Chemistry                             fax       (858) 558 2872
 ACADIA Pharmaceuticals
 3911 Sorrento Valley Boulevard
 San Diego CA 92121-1402  USA
 dseverance ^at^ acadia-pharm.com
 www.acadia-pharm.com