From chemistry-request@server.ccl.net Fri Mar 8 05:17:16 2002 Received: from fletxa.iqs.es (root@[193.145.86.7]) by server.ccl.net (8.11.6/8.11.0) with ESMTP id g28AHF506155 for ; Fri, 8 Mar 2002 05:17:15 -0500 Received: from edurne.iqs.es (edurne.iqs.url.es [193.145.86.6]) by fletxa.iqs.es (8.9.3/8.9.3) with ESMTP id MAA29082 for ; Fri, 8 Mar 2002 12:20:54 +0100 Sender: rosalia@fletxa.iqs.es Message-ID: <3C4F39A9.594D9B6@edurne.iqs.es> Date: Wed, 23 Jan 2002 23:31:05 +0100 From: Rosalia Pascual X-Mailer: Mozilla 4.7C-SGI [en] (X11; I; IRIX64 6.5 IP30) X-Accept-Language: en MIME-Version: 1.0 To: chemistry@ccl.net Subject: modeling loops of a GPCR Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit We are modeling the loops of a GPCR with the modeller program, however we are having problems with the N- anc C-terminal chains. We have also looked some other programs to model the loops with ab initio methodologies as Rosetta, however we are not quite satisfied with the results. We would be very thankful for some advice about alternative methodologies and programs. Thanks in advance. Rosalia *************************************************************************** Ramon Llull University (www.url.edu) Institut Quimic de Sarria -Organic Chemistry Department Via Augusta 390 08017- Barcelona, Spain Tel.: +34-93-267.20.00 ***************************************************************************