CCL: CAS number to Smile String





On Thu, Sep 10, 2009 at 12:27 PM, Chunhui Li baotogo2004#,#gmail.com <owner-chemistry~~ccl.net> wrote:

Sent to CCL by: "Chunhui  Li" [baotogo2004_._gmail.com]
Hi Dear ALl,

I want to generate smile strings for more than 100 chemicals. All I have is the CAS number for each chemical. Is there any tools I can use to do this automatically?

One way to get it is to use the PubChem synonym tables - this is obviously not a comprehensive solution as it doesn't contain the entire CAS registry.

There's a simple REST interface (based on a mirror of PubChem at IU). For example, given a CAS for aspirin visit

http://toposome.chemistry.drexel.edu/~rguha/rest/db/pubchem/cas2smi/69-46-5

and you get back the SMILES for it. In general, replace the CAS at the end of the URL to whatever you want




--
Rajarshi Guha
NIH Chemical Genomics Center