CCL: Negative NMODE

From: Kshatresh Dutta Dubey <kshatresh|*|gmail.com>
Subject: CCL: Negative NMODE
Date: Tue, 6 Apr 2010 17:05:04 +0530

Dear All,

During the calculation of binding free energy i got negative entropic contribution (NMODE= negative). Can entropic contributions be negative, and what is the significance of it?

Every help is welcome. Thanks in advance.

Regards

kshatresh