Bio.com Life Sciences News Update
October 2, 2002
Produced by Bio Online(r)
Portal to the Life Sciences(tm)
www.bio.com | www.bioprotocol.com
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CONTENTS:
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1. Science News: "Wrong Proteins Targeted in Cancer Research?"
2. InFocus: "Protein Informatics: Turning Data Into Knowledge"
3. Career Center: Job Searching Just Got Easier!
4. Jobs of the Week: "Research Scientist, Immunochemistry" and more
5. Featured Employer: Wyeth
6. Featured Books: "PDQ Physiology" and other titles
7. Market Research: "Drugs of Tomorrow: Cancer Overview" and others
8. Featured Software: "Beacon Designer 2" and more
9. Featured Lab Equipment: "Digital Orbital Shaker 100"
10. Company Profiles: Submit your FREE Company Profile!
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1. SCIENCE NEWS
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-Wrong Proteins Targeted in Cancer Research?
http://www.bio.com/jump.jhtml?id=1000016
Researchers may be looking for novel cancer drugs in the wrong places,
says Rockefeller University Professor James E. Darnell, Jr., M.D.,
in an article in this month's Nature Reviews Cancer. Darnell, who
received the 2002 Albert Lasker Award for Special Achievement in
Medical Science, argues that drug development research should focus
more on a specific group of proteins - called transcription
factors - known to be overactive in almost all human cancers.
-Macrophages Can Cause Lymphoma
http://www.bio.com/jump.jhtml?id=1000017
UCSF researchers have found that macrophages, when taken from
HIV-infected lymphoma patients and injected into mice, induced
aggressive mouse T-cell lymphomas in the mice. Macrophages from
healthy donors did not. "This research establishes that macrophages
can cause disease as opposed to current dogma that asserts that the
purpose of these cells is benevolent, solely to assist in fighting
disease," said the study's lead investigator, Michael S. McGrath.
-First Computer Model of E-coli Ribosome
http://www.bio.com/jump.jhtml?id=1000018
Researchers at the Department of Energy's Los Alamos National
Laboratory have created the first computer model of a key part
of the E-coli ribosome, a cellular structure responsible for the
creation of proteins, which has applications in the development of
new and powerful antibiotics for use in the treatment of illnesses
caused by all pathogens, including a host of bioweapons agents.
-Fragile X Syndrome May be Linked to RNAi
http://www.bio.com/jump.jhtml?id=1000019
Two independent research groups have discovered that the Drosophila
version of the human fragile X mental retardation protein associates
with components of the RNAi pathway, suggesting that the molecular
mechanism underlying fragile X syndrome may involve an RNAi-related
process.
-New Technique for Screening Tumors
http://www.bio.com/jump.jhtml?id=1000020
With the help of data from the Human Genome Project, UCSF scientists
have developed a new technique for screening tumors that highlights
the role of a non-genetic mechanism in cancer. The researchers say
the approach, which they applied to the study of human brain tumors,
"widens the lens" on the cancer genome, and could lead to new
therapeutic targets.
-Protein Signals Influence Elephant Mating
http://www.bio.com/jump.jhtml?id=1000021
In a study that may improve animal breeding and reveal more about how
animals detect odors, Utah and Oregon scientists learned how proteins
help a female sex attractant stimulate male elephants so they mate,
and how one protein may end their arousal.
-FEATURE: From Femtosecond Physics to Yeast Genetics
http://www.bio.com/jump.jhtml?id=1000022
Rene Descartes once remarked that as a young man, he read every book
he could get his hands on - literally. The absurdity of making such
a statement today is a measure of the immense explosion of information
in the last few centuries. This explosion of information has had
a paradoxical effect on modern science. The more we know, the
less aware we become of what we know. Disciplines have become so
specialized that it is difficult to keep abreast of the discoveries
in one sub-specialty, let alone several fields.
To view Industry news, visit:
http://www.bio.com/jump.jhtml?id=1000001
To view Research news, visit:
http://www.bio.com/jump.jhtml?id=1000002
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2. INFOCUS WEBCAST
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1) "Protein Informatics: Turning Data Into Knowledge"
Broadcast Wednesday, September 25, 2002
*Click here to listen to the audio recording:
http://www.bio.com/jump.jhtml?id=1000003
*Click here to enter a drawing for a giveaway from our sponsors:
http://www.bio.com/jump.jhtml?id=1000004
*To view all past InFocus Webcast recordings and transcripts, go to:
http://www.bio.com/jump.jhtml?id=1000005
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3. CAREER CENTER
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Tired of searching for a job day after day?
Let Bio.com do the job search for you!
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As a Bio.com Member, you will also enjoy Bio.com's new Career Center
Tool that allows you to:
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-Receive Job Agent alerts for jobs that match your criteria
-Apply for jobs with a one click application process
-Maintain/store your resume confidentially
-Receive monthly e-newsletter with "Featured Jobs" and "Featured
Employers"
These services are FREE for you to use. So, what are you waiting for?
Sign up for your Bio.com Membership and start your job search today!
http://www.bio.com/jump.jhtml?id=1000007
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4. JOBS OF THE WEEK
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1. PPD: Research Scientist, Immunochemistry
http://www.bio.com/jump.jhtml?id=1000010
2. Rosetta Biosoftware: Director of Marketing
http://www.bio.com/jump.jhtml?id=1000008
3. Protea Biosciences: Bioinformatics Databases Manager
http://www.bio.com/jump.jhtml?id=1000023
4. Ingenuity Systems: Computational Biologist
http://www.bio.com/jump.jhtml?id=1000009
5. Syntonix Pharmaceuticals: Manufacturing and Process Development Manager
http://www.bio.com/jump.jhtml?id=1000024
6. Par Pharmaceuticals: Senior Regulatory Affairs Associate
http://www.bio.com/jump.jhtml?id=1000025
7. Sunesis: Research Associate
http://www.bio.com/jump.jhtml?id=1000011
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5. FEATURED EMPLOYER
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Wyeth is a Fortune 500 global enterprise servicing the health needs of
people in more than 145 countries. Achieving over $14 billion in net
revenue in 2001, Wyeth provides more prescription products to Americans
than any other pharmaceutical company and offers one of the broadest
and most diverse product lines in the industry. We are the leader in
women's health care research and marketing and are among the top
manufacturers of vaccine products in the United States. For current
openings go to:
http://www.bio.com/jump.jhtml?id=1000038
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6. FEATURED BOOKS - NEW!
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Bio.com NOW offers an extensive selection of Life Science related books.
Check out these best selling titles in the Bio.com Store:
-PDQ Physiology
http://www.bio.com/jump.jhtml?id=1000026
PDQ Physiology offers a concise, up-to-date summary of human
physiology. It is an ideal resource for the more advanced physiology
specialist and health professional requiring a quick view or review.
The book's perspective is one of integration while incorporating the
current understanding in molecular and cellular physiology and offers
up-to-date explanations of physiological phenomena.
-Telomeres and Telomerase: Methods and Protocols
http://www.bio.com/jump.jhtml?id=1000027
John A. Double and Michael J. Thompson have collected a critically
important series of novel and essential techniques for studying
telomeres and telomerase. These readily reproducible methods provide
cutting-edge tools to identify, measure and analyze telomeres, to
determine telomerase expression at the RNA level, to determine
telomerase activity, and to detect potential modifiers of this activity.
-Biodiversity Dynamics
http://www.bio.com/jump.jhtml?id=1000028
How will patterns of human interaction with the earth's eco-system
impact on biodiversity loss over the long term - not in the next ten or
even fifty years, but on the vast temporal scale be dealt with by earth
scientists? Biodiversity Dynamics is divided into two parts, the first
exploring turnover at the species level and the second investigating
larger-scale community and ecosystem turnover.
Click here to browse through our books catalogue:
http://www.bio.com/jump.jhtml?id=1000029
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7. MARKET RESEARCH
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Bio.com offers the most comprehensive collection of market research.
-Drugs of Tomorrow: Cancer Overview
http://www.bio.com/jump.jhtml?id=1000030
The oncology market will show dramatic development in both overall size
and content over the next decade. As the value of the market for
traditional therapies is driven down, and more innovative therapies are
launched, pharmaceutical companies will need to adapt their product
development and marketing strategies. Datamonitor's Drugs of Tomorrow:
Cancer Overview analyses the current state and future trends in the
cancer market, with reference to both treatment classes and dominant
companies.
-The Outlook For Direct-To-Consumer Marketing: Maximizing The Return
On Your Investment
http://www.bio.com/jump.jhtml?id=1000031
This report focuses on key issues in Direct-to-Consumer (DTC) marketing
that have emerged since the FDA relaxed its guidelines on broadcast
advertising. Principally, the difficulties of measuring return on
investment for DTC marketing are analyzed and the report offers
recommendations for optimizing companies' investment.
-The Dynamic Antibody Industry including Polyclonals and Monoclonals
http://www.bio.com/jump.jhtml?id=1000032
Antibody-based drugs, in particular monoclonal antibody-based products,
began to enter the market in earnest in the late 1990s. In 2002,
antibodies were the single largest class of therapeutics in clinical
development with the exception of vaccines. The aim of this report is
to provide a range of information - from detailed market analyses through
industry trends - to quantify and qualify the emerging market for
monoclonal and polyclonal antibody drugs.
Click here to browse through our publications catalogue:
http://www.bio.com/jump.jhtml?id=1000013
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8. FEATURED SOFTWARE
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Bio.com offers a very comprehensive selection of Life Science related
software. Check out these latest additions:
-Beacon Designer 2
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Molecular beacon, TaqMan(r) probe and primer pair design software for
Windows. Design real time PCR probes and primer pairs with a click of a
button. Designs beacons free of dimers, repeats and runs for increased
signal strength. Avoids cross homologies with all primers preventing
competition in multiplex reactions. Designs molecular beacons for
detection of both wild and mutant alleles.
-Fusion pro
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D.o.E. FUSION combines advanced Data Mining Technology with state-of-
the-art Design of Experiments capabilities in an extremely simple to
operate graphical interface. It's advanced capabilities far exceed
those available in any software package featuring Design of Experiments
(D.o.E.) methods.
-ACD/ChemSketch with Dictionary
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ACD/ChemSketch is an integrated software package for drawing chemical
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Click here to browse through our software catalogue:
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9. FEATURED LAB EQUIPMENT - NEW!
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Bio.com now offers Lab Equipment at the Bio.com Store:
-Digital Orbital Shaker 100
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Key features include: 1. Microprocessor based keypad with digital
display of preset time, continuous run and RPM indicator. 2. Aluminum
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independently from each other.
Click here to browse through our lab equipment catalogue:
http://www.bio.com/jump.jhtml?id=1000037
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10. COMPANY PROFILES
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Life science organizations are offered the opportunity to place a
Company Profile on the Bio.com site for free!
"Company Profiles" is a searchable database accessible to all Bio.com
users as well as your customers, collaborators, potential employees
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This free service affords your company an excellent opportunity to
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To submit a company profile to Bio.com, click here:
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Click here to browse through our Company Profile Directory:
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Copyright (c) 2002 Bio Online, Inc. All rights reserved.
Received on 2002-10-02 - 07:44 GMT
This archive was generated by hypermail 2.2.0 : 2005-11-24 - 10:21 GMT