QSAR - Life Sciences News Update

From: Bio.com / Bio Online <newsletter:bio.com>
Date: Wed, 21 Aug 2002 02:32:11 -0700 (PDT)

Bio.com Life Sciences News Update
August 21, 2002

Produced by Bio Online(r)
Portal to the Life Sciences(tm)
www.bio.com | www.bioprotocol.com

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CONTENTS:
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1. Science News: "Inducing Cancer Cell Death"
2. InFocus: "Cellular Signaling" - Listen to what the experts have to say
3. Featured Event: "World Genomics Symposium"
4. Career Center: Biotech Job Fair - September 18th, 2002
5. Jobs of the Week: "Research Scientist" and others
6. Market Research: "High-Throughput Screening" and others
7. Featured Software: "Genamics Expression 1.1" and others

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Newsletter Sponsored by: Applied Biosystems
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Free Technical Seminar from Applied Biosystems

You are invited to hear how Applied Biosystems is leading the
next generation of life science research with new technologies
and services at a one-day event. Registration for this national
seminar, refreshments and lunch are complimentary. Please
reserve your place today, as seating is limited.
http://events-na.appliedbiosystems.com/mk/submit/0719_ARDC?_JS=T&rd=t

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1. SCIENCE NEWS
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-How Herpes Tricks the Immune System
http://www.bio.com/jump.jhtml?id=300001
Herpes viruses enter the body and hide away in cells, often re-emerging
later to cause illnesses such as shingles, genital herpes and cancer. How
these viruses evade the immune system remains poorly understood, but
researchers at Washington University School of Medicine in St. Louis
discovered that a mouse herpes virus uses molecules that mimic a cell's
own proteins to help thwart an immune attack.

-Inducing Cancer Cell Death
http://www.bio.com/jump.jhtml?id=300002
A new technique for tricking cancer cells into "committing suicide" and
thus preventing their spread has been developed by researchers at the
Hebrew University of Jerusalem. Their work is described in the September
issue of Nature Biotechnology, which was published this week in its
Internet version. The technique involves the engineering of a virus that
will induce the cancer cell to behave in a manner similar to that of
normal cells that are under attack.

-Promising Multi-Strain HIV Vaccine Candidate
http://www.bio.com/jump.jhtml?id=300003
AIDS researchers have developed a candidate vaccine strategy that, for
the first time, demonstrates an ability to elicit antibodies that block
the infection of multiple HIV virus strains -- an elusive scientific
goal that has been pursued for a decade.

-Emulating Nature to Build Designer Polymers
http://www.bio.com/jump.jhtml?id=300004
Future designer polymers may be assembled like children's Lego toys
using modular polymer scaffolds programmed to attract building blocks
of small molecules. Weak and easily reversed chemical interactions
would self-assemble those molecules to form complex structures with
predictable physical and chemical properties.

-Gene That Triggers Pancreas Formation
http://www.bio.com/jump.jhtml?id=300005
Before the pancreas is a pancreas, it is just two tiny bumps -- two
groups of cells sprouting from a central tube. What makes these cells bud
off from the main group? How do they go on to make all the cell types of
the mature pancreas? These are the kinds of questions that drive the
research efforts of Vanderbilt developmental biologist Chris Wright and
colleagues. The answers could pave the way toward limitless supplies of
pancreatic cells for transplantation therapy of diabetes.

-FEATURE: Outside View: Killing the Golden Goose
http://www.bio.com/jump.jhtml?id=300006
The American pharmaceutical industry now produces any number of
miracle drugs that are saving lives and dramatically improving the
lives of those suffering from debilitating diseases. Several provisions
in the pending Medicare drug bill threaten to cut off the funding that
makes these modern biomedical miracles possible.

-FEATURE: Robot Streamlines Protein Analysis
http://www.bio.com/jump.jhtml?id=300007
To learn more about life, Berkeley Lab researchers rely on robots. They've
automated a traditionally slow process in which tiny protein crystals are
mounted and centered in an x-ray beam and analyzed for their molecular
structure. The robot, which is the first such device available to general
users at a synchrotron, both mounts protein crystals in a beamline and
uses the resulting data to decipher the protein's atomic makeup.

To view Industry news, visit:
http://www.bio.com/jump.jhtml?id=300008

To view Research news, visit:
http://www.bio.com/jump.jhtml?id=300009

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2. INFOCUS WEBCAST
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1) "Cellular Signaling"
Broadcast Thursday, August 1, 2002

*Click here to listen to the audio recording:
http://www.bio.com/jump.jhtml?id=300010

*Click here to enter a drawing for a giveaway from our sponsors:
http://www.bio.com/jump.jhtml?id=300011

*To view all past InFocus Webcast recordings and transcripts, go to:
http://www.bio.com/jump.jhtml?id=300012

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3. FEATURED EVENT: WORLD GENOMICS SYMPOSIUM
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Join over 2,000 life science colleagues at World Genomics Symposium
and Exposition, September 18-20, 2002 at the new Atlantic City
Convention Center. Register at http://www.world-genomics.com for
FREE Expo and Poster Presentation admittance when you enter
priority code BIO2 before September 7. Same Priority Code gets
you $50 off Conference Admittance in a 60+ session program!

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4. CAREER CENTER
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BIOTECH JOB FAIR....
Presented by Bio.com and the San Francisco Chronicle.

IMAGINE the Biggest names in BIOTECH and you are invited to meet them all!

Bay Area biotech and pharmaceutical companies come to this Job Fair to
seek out the most talented life sciences professionals like you.

Attend the Biotech Job Fair and meet face-to-face with top recruiters
and hiring managers in the industry.

This is an exciting event that you can't afford to miss!

Location: South San Francisco Convention Center
Date: Wednesday, September 18th, 2002
Time: 1:00 pm - 6:00 pm

For more information and to pre-register for the job fair, please go to
http://www.bio.com/jump.jhtml?id=300013

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5. JOBS OF THE WEEK
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Look at what's new in the Bio.com Career Center this week:

1. Celera Genomics: Scientist
http://www.bio.com/jump.jhtml?id=300014

2. The Burnham Institute: Scientist
http://www.bio.com/jump.jhtml?id=300015

3. Arete Associates: Research Scientist
http://www.bio.com/jump.jhtml?id=300016

4. Gilead Sciences: Project Manager
http://www.bio.com/jump.jhtml?id=300017

5. Affymetrix: Staff Scientist
http://www.bio.com/jump.jhtml?id=300018

6. Essential Therapeutics: Research Associate
http://www.bio.com/jump.jhtml?id=300019

Register today and start using our new features:
http://www.bio.com/jump.jhtml?id=300020

Click here to browse all jobs from Bio.com's Career Center:
http://www.bio.com/jump.jhtml?id=300021

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6. MARKET RESEARCH
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Bio.com offers the most comprehensive collection of market research.

-Healthcare Venture Capital Report (2Q 02)
http://www.bio.com/jump.jhtml?id=300022
Growthink's Healthcare Venture Capital Report (2Q 02) analyzes and profiles
the 162 healthcare companies that raised venture capital in the second
quarter of 2002 (representing $2 billion) and more than 85 investors that
funded two or more healthcare ventures. All company and investor profiles
include complete contact information. The report is organized by 5 key
sectors: Biotechnology/Pharmaceutical, Diagnostic/Patient Care, Healthcare
Software & Services, Healthcare Content & Commerce and Medical Devices.

-High-Throughput Screening (HTS)
http://www.bio.com/jump.jhtml?id=300023
Microplate technology allows both miniaturization and high-throughput to
merge in an effort to streamline the drug discovery process, which is
critical to the pharmaceutical industry. Microplate readers allow
researchers to perform a variety of different assays efficiently and
precisely as a result of their high-throughput adaptability and robotics.
Although the microplate reader market is well established, it is expanding
due to the dynamic nature of the platform. The investigation of end-user
needs in High-Throughput Screening (HTS) can be leveraged across several
product categories with the goals of developing better products and
expanding market penetration.

-Overcoming Formulations Challenges: Novel Techniques for Optimum Results
http://www.bio.com/jump.jhtml?id=300024
Up to 40% of molecules currently emerging from drug discovery are either
insoluble or poorly soluble. A record number of biological products are
under development, increasing the demand for improved formulations that
address their specific challenges. These new drugs, including peptides,
proteins, monoclonal antibodies and gene-based products, tend to be
unstable in aqueous form and tend to be very sensitive to heat, pressure
and other environmental conditions. D&MD's Overcoming Formulation
Challenges examines current and emerging technologies that are essential
to formulating insoluble small molecules.

Click here to browse through our publications catalogue:
http://www.bio.com/jump.jhtml?id=300025

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7. FEATURED SOFTWARE
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Bio.com offers a very comprehensive selection of Life Science related
software. Check out these latest additions:

-NMR-Spectral Assignment Made Simple (NMR-SAMS)
http://www.bio.com/jump.jhtml?id=300026
Designed to work like a human spectroscopist, NMR-SAMS is an excellent
tool for structure elucidation of completely unknown or partially-known
small molecules (having less than 128 Carbons), for validating proposed
structures, and can also be used to automatically generate resonance
assignments of known structures. Advanced report generation tools allow
the user to copy and paste molecules and assignment tables. Exports
structure files (mol, mdl and sdf) with attached assignment tables, and
creates spectral correlation tables which can easily be placed into word
processing documents for successful report generation.

-ChemDraw Ultra 7.0
http://www.bio.com/jump.jhtml?id=300027
ChemDraw is the industry leader of chemical drawing programs. This
ultimate drawing suite includes ChemDraw Ultra 7.0, Chem3D Pro 7.0 and
ChemFinder Pro 7.0. It adds BioArt, an improved ChemDraw for Excel,
Name=Struct, AutoNom, ChemNMR, and SDK features, as well as the Chem3D
and ChemFinder applications and the Chem3D Plugin, to ChemDraw Pro.

-Genamics Expression 1.1
http://www.bio.com/jump.jhtml?id=300028
Genamics Expression is a revolutionary new Windows application for DNA
and protein sequence analysis. Utilizing a novel interface, Expression
makes complex computational analyses of sequence information incredibly
simple. The coupling of creative innovations with the very latest
computing technology defines Expression as the new gold standard in
computational sequence analysis.

Click here to browse through our software catalogue:
http://www.bio.com/jump.jhtml?id=300029

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Copyright (c) 2002 Bio Online, Inc. All rights reserved.
Received on 2002-08-21 - 05:18 GMT

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