THIS INFORMATION IS OBSOLETE AND IS PROVIDED ONLY FOR ITS HISTORICAL VALUE

by R. D. Blake, Department of Biochemistry, and Gary R. Day, Department of Mathematics, University of Maine, Orono, Maine 04469

QCPE 475 is essentially a package of programs which carries out the following analyses and manipulations:

AMINOS: Analyzes a DNA sequence to obtain information concerning the proteins it contains. DOMAIN: Seeks out segments which possess a given G-C content. GCPLOT: Plots the G-C content as a function of position and window size. GCTOT: Calculates the base content and variances of each base and GC and AT as well as the correlation coefficients of A,C,G, and T. INVERT: Scans the sequence in search of homologies between the primary and complementary strands. LIST:Creates a numbered listing of the sequence. MATCH: Searches an entire sequence for homologies. MIRROR: Searches for mirror-image palindromes and pseudo-palindromes. NTUPLE: Calculates the triplets of a given size in one or more DNA sequences and calculates their relative and expected frequencies. PALIND: Performs true twofold symmetry analysis in searchof palindromesand pseudopalindromes. COMPARE: Compares two DNA sequences in search of identical segments. ENZYME: Reads enzyme names and recognition patterns from a file and searches for cleavage sites in a sequence. TUPGRAPH: Plots information regarding the occurrence of triplets in a DNA sequence.

FORTRAN IV (IBM G-Level) Lines of Code: 4586